Search for dissertations about: "allelotyping"

Found 3 swedish dissertations containing the word allelotyping.

  2. 1. Interrogation of Nucleic Acids by Parallel Threading

    Author : Erik Pettersson; Joakim Lundeberg; Afshin Ahmadian; Ann-Christine Syvänen; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; genotyping; multiplex amplification; trinucleotide threading; single nucleotide polymorphism; genotype calling; Expectation-Maximization; protein-epitope signature tag; expression profiling; Human Protein Atlas; pooled genomic DNA; Pyrosequencing; 454; allelotyping; association studies; bioinformatics; Bioengineering; Bioteknik;

    Abstract : Advancements in the field of biotechnology are expanding the scientific horizon and a promising era is envisioned with personalized medicine for improved health. The amount of genetic data is growing at an ever-escalating pace due to the availability of novel technologies that allow massively parallel sequencing and whole-genome genotyping, that are supported by the advancements in computer science and information technologies. READ MORE

  4. 2. Parallel target selection by trinucleotide threading

    Author : Pawel Zajac; Joakim Lundeberg; Afshin Ahmadian; Mats Nilsson; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; trinucleotide threading; multiplex amplification; expression profiling; microarray; generic tag; short tandem repeat; microsatellite; electrophoresis; single nucleotide polymorphism; allelotyping; 454; Pyrosequencing; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : DNA is the code for all life. Via intermediary RNA the information encoded by the genome is relayed to proteins executing the various functions in a cell. Together, this repertoire of inherently linked biological macromolecules determines all characteristics and features of a cell. READ MORE

  5. 3. Molecular genetic studies on gliomas and capillary hemangioblastomas of the central nervous system

    Author : Guido Reifenberger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The molecular genetic alterations associated with the initiation and progression of central nervous system tumors are complex and poorly understood at present. This thesis aims at the further elucidation of the molecular genetics of two important types of central nervous system tumors: gliomas and capillary hemangioblastomas. READ MORE