Search for dissertations about: "alpha-2-adrenergic agonist"

Found 3 swedish dissertations containing the words alpha-2-adrenergic agonist.

  1. 1. Experimental Injury to the Visual System : Molecular Studies of the Retina

    Author : Ulrika Lönngren; Finn Hallböök; Fredrik Ghosh; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retina; injury; ischemia; gene expression; brimonidine; alpha-2-adrenergic agonist; neuroprotection; growth factors; apoptosis; Müller cells; Neuroscience; Neurovetenskap;

    Abstract : Retinal ganglion cells play a crucial role in the relay of visual signals from the eye to the brain. This cell type is affected and eventually lost in the eye disease glaucoma, resulting in progressive and irreversible loss of vision. READ MORE

  2. 2. Islet glucose metabolism and insulin release in two animal models of glucose intolerance

    Author : Zong-Chao Ling; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Goto-Kakizaki GK rat; transgenic mice; glucose-6-phosphatase activity; insulin secretion; glucocorticoids; [alpha]2-adrenergic receptors; hyperglycemia;

    Abstract : Type 2 diabetes is a complex and heterogenous disease resulting from the interaction of defects of both genetic and environmental origin. Abnormalities contributing to the pathogenesis of type 2 diabetes include impaired [beta]-cell function, peripheral insulin resistance and increased hepatic glucose production. READ MORE

  3. 3. Anaesthesia and analgesia for surgery in rabbits and rats : a comparison of the effects of different compounds

    Author : Patricia Hedenqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Studies of anaesthesia and analgesia in rats and rabbit were undertaken with the aim to improve anaesthesia techniques, for better animal welfare and research quality. Induction of anaesthesia with the volatile halogenated agents isoflurane, sevoflurane and desflurane was compared in the New Zealand White rabbit. READ MORE