Search for dissertations about: "alternative promoters"

Showing result 1 - 5 of 32 swedish dissertations containing the words alternative promoters.

2. 1. Molecular mechanisms of alternative estrogen receptor signaling

   Author : Linda Björnström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Estrogen is a key regulator of growth, differentiation and function in a broad range of target tissues, including the male and female reproductive tracts, mammary gland, bone, brain and the cardiovascular system. The biological effects of estrogen are mediated through estrogen receptor a (ERalpha) and estrogen receptor beta (ERbeta), which belong to a large superfamily of nuclear receptors that act as ligand-activated transcription factors. READ MORE

4. 2. Towards the enhanced applicability of cold mix asphalt: : An experimental study focusing on surface free energies and the breaking and coalescence of bitumen emulsions

   Author : Abdullah Khan; Nicole Kringos; Per Redelius; Andreas Loizos; KTH; []
   Keywords : Bitumen; Cold Asphalt Mixtures; Minerals Aggregates; Surface Free Energy; Sorption; Contact Angle; Bitumen Emulsions; Breaking and Coalescence; Emulsifiers; Adhesion Promoters.; Bitumen; kallblandad asfalt; mineraler aggregat; fri ytenergi; sorption; kontaktvinkel; Bitumenemulsioner; brytning och koalescensen; emulgatorer; adhesionsegenskaper; Byggvetenskap; Civil and Architectural Engineering;

   Abstract : The environmental, social and economic sustainability of our infrastructure network is clearly of paramount importance to the road-engineering sector as well to society at large. Sustainable road materials and reduced transport of those materials therefore play a significant role. READ MORE

5. 3. New insight into myocardin regulation and function in smooth muscle cells

   Author : Li Liu; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alternative splicing; Contractility; Inflammation; Muscarinic receptor; Myocardin-related transcription factors; Phenotypic modulation; Smooth muscle; SRF; WWTR1; YAP1;

   Abstract : Smooth muscle cells (SMCs) are constituents of hollow inner organs. Their contractile function governs essential physiological functions, such as breathing, eating, blood pressure control, urination, and childbirth. READ MORE

6. 4. Expression of thioredoxin reductase 1 in mammalian cells with regulation by the core promoter and use of alternative splice variants

   Author : Anna-Klara Rundlöf; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Redox regulation; thioredoxin reductase; TXNRD1; selenoprotein; promoter; transcription; alternative splicing; expression;

   Abstract : Reactive oxygen species are generated in cells as by-products of aerobic metabolism. To protect from damaging effects the cells possess several antioxidant systems and one of the most important is the thioredoxin system. READ MORE

7. 5. The estrogen receptor gene : promoter organization and expression

   Author : Kaj Grandien; Karolinska Institutet; Karolinska Institutet; []
   Keywords : estrogen receptor; alternative promoters; gene expression; translation;

   Abstract : The estrogen receptor (ER) is a ligand-activated transcription factor and a member of a large family of nuclear hormone receptors. As a mediator of estrogen hormone action, the ER is involved in many important physiological processes. ER gene expression has been demonstrated to be restricted to certain tissues and under complex hormonal control. READ MORE