Search for dissertations about: "amiloride-sensitive sodium channels"

Found 4 swedish dissertations containing the words amiloride-sensitive sodium channels.

  1. 1. Development and regulation of alveolar fluid clearance in the guinea pig

    Author : Andreas Norlin; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; oxytocin-induced preterm labor; IRDS; fetal lung fluid; preterm lung development; amiloride-sensitive sodium channels; beta-adrenergic stimulation; alveolar epithelium; Animal physiology; Djurfysiologi;

    Abstract : Alveolar fluid clearance is driven by active absorption of Na+ across the alveolar epithelium. Development and hormonal regulation of alveolar fluid clearance over 1 hour was studied by instillation of a protein-containing, isosmolar fluid into lungs of fetal, newborn, and adult guinea pigs. READ MORE

  2. 2. Expression and regulation of water channels and ion transporters : ontogenic aspects

    Author : Masato Yasui; Karolinska Institutet; Karolinska Institutet; []
    Keywords : water balance; developmental gene expression regulation; gene transcription; fetal lung fluid; urinary concentrating capacity; hormonal regulation;

    Abstract : The content and distribution of body water changes dramatically during the perinatal period and in infancy. Transport of water across the cell membrane occurs via diffusion and via specific water channels. Transport via water channels is fast and may be hormonally regulated. READ MORE

  3. 3. Role of ion and water channels for lung growth in congenital diaphragmatic hernia

    Author : Andreas Ringman Uggla; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Early lung development is based on a continuous cross-talk of growth and transcription factors between the developing lung bud and the surrounding parenchyma. Throughout fetal life, pulmonary growth and differentiation depend on Cl- driven lung liquid secretion. READ MORE

  4. 4. Alpha1-Antitrypsin: New insights into the biological role in vitro and in vivo

    Author : Izabela Nita; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Alpha1-Antitrypsin (AAT), an acute-phase glycoprotein produced predominantly in the liver by hepatocytes, but also by macrophages, pulmonary alveolar cells and intestinal epithelial cells, is a member of the SERPIN superfamily (SERine Protease INhibitors), and is one of the major inhibitors of neutrophil elastase in human plasma. Although AAT plays a critical role in regulating inflammation by inhibiting neutrophil serine proteases, recent studies suggest that AAT exhibits much broader anti-inflammatory activity. READ MORE