Search for dissertations about: "angiotensin II receptor"

Showing result 1 - 5 of 95 swedish dissertations containing the words angiotensin II receptor.

  2. 1. Synthesis of Aldehyde-Functionalized Building Blocks and Their Use for the Cyclization of Peptides : Applications to Angiotensin II

    Author : Petra Johannesson; Rob M. J. Liskamp; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Synthesis; Aldehyde; Cyclization; Peptide; Angiotensin II; Ang II; Bioactive Conformation; Solid Phase Peptide Synthesis; Dimethyl Acetal; Farmaceutisk kemi; Syntes; Aldehyd; Cyklisering; Peptid; Bioaktiv konformation; Fast-fas peptidsyntes; Dimetylacetal; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

    Abstract : This study addresses the issue of how to convert peptides into drug-like non- peptides with retained biological activities at peptide receptors. Angiotensin II (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, Ang II) was used as a model peptide. READ MORE

  4. 2. Vascular Endothelin and Angiotensin Receptors Regulation in Inflammatory Arterial Disorders

    Author : Ivan Dimitrijevic; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ischemic heart disease; resistance artery; giant cell arteritis; temporal artery; immunohistochemistry; AT2 receptor; AT1 receptor; Endothelin-1; ETA receptor; ETB receptor;

    Abstract : The present thesis is aimed to examine the hypothesis that the degree of vascular inflammation correlates with the expression of vascular endothelin and angiotensin receptors. The receptor changes were studied in subcutaneous resistance arteries in patients with different degrees of ischemic heart disease (IHD). READ MORE

  5. 3. On angiotensin II receptor type 2 receptors in the small intestine

    Author : Sara Ewert; Göteborgs universitet; []
    Keywords : renin-angiotensin; angiotensin; small intestine; mucosa; epithelium; AT1; AT2; bradykinin; BK2 receptor; nitric oxide; iNOS; smooth muscle; contractility;

    Abstract : The endocrine renin-angiotensin system (RAS) is important in the regulation of extracellular fluid volume and systemic blood pressure in strenuous conditions such as hypovolemia. Also present locally in peripheral tissues, all components of RAS are expressed and have been shown to modulate development, cell growth and inflammation. READ MORE

  6. 4. Vascular receptor changes in ischemic stroke

    Author : Emelie Stenman; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular receptor changes; Ischemic stroke; Endothelin; Angiotensin; Cardiovascular system; Kardiovaskulära systemet; Pharmacological sciences; pharmacognosy; pharmacy; farmakognosi; farmaci; toxikologi; toxicology; Farmakologi;

    Abstract : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. READ MORE

  7. 5. Angiotensin II Receptors in the Human Coronary Circulation and in Heart Failure

    Author : Emil Pantev; Kardiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; Heart Failure; Human Coronary Arteries; Angiotensin II; AT receptors;

    Abstract : Angiotensin II (Ang II) is a potent vasoconstrictor that is implicated in the pathogenesis of hypertension, heart failure and atherosclerosis. In this thesis, the efficacy and safety of Ang II receptor blockers (ARB) were evaluated. READ MORE