Search for dissertations about: "anti inflammatory activity insulin"

Showing result 1 - 5 of 18 swedish dissertations containing the words anti inflammatory activity insulin.

  2. 1. Post-transplantation Hypercholesterolaemia

    Author : Osama Al Rayyes; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thiazolidinediones; transplantation; low density lipoprotein; insulin; indomethacin; hydrocortisone; fluvastatin; flufenamic acid; Cholesterol; cyclosporine; troglitazone.; Immunology; serology; Immunologi; serologi;

    Abstract : The multidrug regimen, cyclosporine, corticosteroids, and azathioprine, is used in transplantation centres to prevent organ rejection. Several clinical studies have shown that cyclosporine and corticosteroids to cause increases in low density lipoprotein (LDL)-cholesterol, with subsequent development of atherosclerosis. READ MORE

  4. 2. Regulation of IL-6-signaling and inflammatory response – Role of insulin, FOXO1 and PKCδ

    Author : Emelie Wallerstedt; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2-Diabetes; inflammation; obesity; IL-6; STAT3; PKCδ; FOXO1;

    Abstract : The aim of this thesis was to investigate if and how insulin antagonizes interleukin-6 (IL-6)-signaling and action using both 3T3-L1 mouse adipocytes (Paper I) and HepG2 human hepatocytes (Paper III). We also investigated the importance of PKCδ in 3T3-L1 adipocytes and mouse embryonic fibroblasts (MEFs) lacking protein kinase C-δ (PKCδ-/-) (Paper II). READ MORE

  5. 3. The cholinergic anti-inflammatory pathway and heart rate variability with special reference to dialysis and renal denervation

    Author : Marie Hilderman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: The Cholinergic Anti-inflammatory Pathway (CAP) is a nerve-mediated circuit through which the vagus nerve regulates the activity of the inflammatory immune response. Injury, ischemia or infection activate the afferent vagus. In the medulla oblongata. READ MORE

  6. 4. Metabolic Aspects in the Polycystic Ovary Syndrome

    Author : Åsa Maria Lindholm; Inger Sundström Porormaa; Mari Bixo; Mats Eliasson; Jan Brynhildsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PCOS; prevalence; fibrinolysis; inflammatory markers; over weight; Obstetrics and gynaecology; Obstetrik och gynekologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of childbearing age and is associated with a number of metabolic disturbances. It has been hypothesised these women carry an increased risk of developing cardiovascular diseases (CVD) with advancing age. READ MORE

  7. 5. Anti-Diabetic and Beta-Cell Protective Actions of Imatinib Mesylate

    Author : Robert Hägerkvist; Nils Welsh; Åke Lernmark; Uppsala universitet; []
    Keywords : Cell biology; Cellbiologi; Diabetes;

    Abstract : Type 1 diabetes is a disease resulting from the progressive immune-mediated destruction of insulin producing β-cells. In order to understand more about diabetes we need to understand the mechanisms governing β-cell death.The leukemia drug Gleevec is a tyrosine kinase inhibitor that targets c-Abl. READ MORE