Search for dissertations about: "anti-TNF-alpha"

Found 4 swedish dissertations containing the word anti-TNF-alpha.

  2. 1. Effect of Drugs on Rabbit Retina

    Author : Anna Cardiakidis Myers; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug toxicity; electroretinography; histopathology; intravitreal injection; rifabutin; anti-VEGF; triamcinolone; benzyl alcohol; anti-TNF-alpha; adalimumab;

    Abstract : The adverse effects of drugs in the eye are not easily detected, and the underlying pathogenesis not fully understood. The effects of four different kinds of drugs have been investigated in the rabbit eye, using electroretinography, ocular examination and histochemical methods. READ MORE

  4. 2. Cytokines in rheumatoid arthritis

    Author : Ann-Kristin Ulfgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Rheumatoid arthritis; Synovitis; Immunohistochemistry; Digital image analysis; Cytokine Therapy; TNF neutralisation; Arthroscopy;

    Abstract : Rheumatoid arthritis (RA) is a chronic systemic disease characterised by inflammation in several joints. Cytokines appear to be important as both disease promoting and disease- suppressing mediators in the disease. READ MORE

  5. 3. Cytokine induced airway hyperreactivity characterized in an in-vitro model of asthma

    Author : Yaping Zhang; Klinisk och experimentell allergiforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; farmakognosi; MAPK; TNF-alpha; 5-HT; Respiratory system; Andningsorganen; Pharmacological sciences; pharmacognosy; pharmacy; interleukin-1beta; hyperresponsiveness; endothelin-1; airway; bradykinin; toxikologi; farmaci;

    Abstract : Asthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. READ MORE

  6. 4. Ureaplasma urealyticum induced pulmonary inflammation in the development of chronic lung disease of prematurity

    Author : Yinghua Li; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic lung disease (CLD) of prematurity is a prolonged respiratory failure in very-lowbirthweight neonates. This disorder is multifactorial and associated with an early increase in the numbers of neutrophils and alveolar macrophages, together with. morphological abnormalities in epithelial and endothelial cells. READ MORE