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Showing result 11 - 15 of 213 swedish dissertations matching the above criteria.

2. 11. Antibiotic Resistance and the Cellular Currency S-adenosyl-methionine : Modification of aminoglycosides and nucleic acids

   Author : Sandesh Kanchugal P; Maria Selmer; Ditlev Brodersen; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibiotic resistance; streptomycin; spectinomycin; X-ray crystallography; methyltransferase; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

   Abstract : Streptomycin and spectinomycin are antibiotics that bind to ribosomes and inhibit protein synthesis. Common resistance mechanisms involve enzymatic modification of the two drugs by aminoglycoside nucleotidyltransferases (ANTs). The first part of this thesis covers the structural mechanism of two ANT enzymes. READ MORE

4. 12. Antibiotic Resistance: A Multimethod Investigation of Individual Responsibility and Behaviour

   Author : Mirko Ancillotti; Stefan Eriksson; Jessica Nihlén Fahlquist; Dan I. Andersson; Alberto Giubilini; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; Behavior; Health Behavior; Health Belief Model; Discrete Choice Experiment; Preferences; Bioethics; Empirical bioethics; Moral responsibility; Justice; Policy demandingness; Virtue ethics; Bioetik; Bioethics;

   Abstract : The rapid development of antibiotic resistance is directly related to how antibiotics are used in society. The international effort to decrease and optimise the use of antibiotics should be sustained by the development of policies that are sensitive to social and cultural contexts. READ MORE

5. 13. Antibiotic resistance in biogas processes

   Author : He Sun; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Anaerobic digestion (AD) is a well-established technology that can play a key role in development of a sustainable society. In AD, organic wastes such as animal manure, food waste and crop residues are used as substrate and converted to biogas and digestate, which represent green energy and a biofertiliser. READ MORE

6. 14. Unpacking Rational Use of Antibiotics : Policy in Medical Practice and the Medical Debate

   Author : Hedvig Gröndal; Tora Holmberg; Ericka Johnson; Uppsala universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Antibiotics; Policy; Medical Sociology; Actor-Network Theory; Human-microbial relations; Antimicrobial Resistance; Everyday Infections; Material semiotics; Medical sociology; Medical objects; Medical technologies; Medical knowledge; Sociologi; Sociology;

   Abstract : Rational use of antibiotics–using antibiotics only when needed and in the right way–is a prioritized goal in policy aimed at preventing antimicrobial resistance. A vast body of research is devoted to understanding why unnecessary antibiotics are prescribed. READ MORE

7. 15. Quantifying effects of antimicrobial drug combinations by modelling and simulation

   Author : Chenyan Zhao; Lena Friberg; Elisabet I. Nielsen; Shampa Das; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics and pharmacodynamics; modelling and simulation; antibiotic combination; model-based translation; antibiotic resistance; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Antibiotic resistance is becoming an accelerating issue, both in the treatment of nosocomial infections and for public health in general. There is a pressing need for innovative methods to understand how available antibiotics could be combined to overcome and limit the emergence of resistance. READ MORE