Search for dissertations about: "antibiotic use"

Showing result 6 - 10 of 213 swedish dissertations containing the words antibiotic use.

  2. 6. Selection of Resistance at very low Antibiotic Concentrations

    Author : Erik Gullberg; Dan I Andersson; Diarmaid Hughes; Linus Sandegren; Laura Piddock; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; Selection; Antibiotic resistant bacteria; Minimal inhibitory concentration; Heavy metals; Conjugative plasmid; ESBL; Mikrobiologi; Microbiology; Biology with specialization in Microbiology; Biologi med inriktning mot mikrobiologi; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

    Abstract : The extensive medical and agricultural use and misuse of antibiotics during the last 70 years has caused an enrichment of resistant pathogenic bacteria that now severely threatens our capacity to efficiently treat bacterial infections. While is has been known for a long time that high concentrations of antibiotics can select for resistant mutants, less is known about the lower limit at which antibiotics can be selective and enrich for resistant bacteria. READ MORE

  4. 7. Development and Stability of Antibiotic Resistance

    Author : Maria Sjölund; Lars Engstrand; Dan Andersson; Pentti Huovinen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; antibiotic resistance; selection; mutation frequency; biological cost of resistance; compensatory evolution; Helicobacter pylori; normal microbiota; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Abstract : Antibiotic resistance is of current concern. Bacteria have become increasingly resistant to commonly used antibiotics and we are facing a growing resistance problem. The present thesis was aimed at studying the impact of antibiotic treatment on pathogenic bacteria as well as on the normal human microbiota, with focus on resistance development. READ MORE

  5. 8. Antibiotic prophylaxis in general oral health care : the perspective of decision making

    Author : Eva Ellervall; Malmö högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic prophylaxis; Decision making;

    Abstract : I Sverige ger läkemedelskommittéerna i landstingen ut rekommendationer för att stödja optimal användning av läkemedel till patienter. Rekommendationerna inkluderar råd om när antibiotika bör användas i förebyggande syfte (antibiotikaprofylax) i tandvården. READ MORE

  6. 9. Acute febrile illness, antibiotic use, and the role of diagnostics to target treatment in India

    Author : Bronwen Holloway; Anna Bergström; Helena Hildenwall; Mats Målqvist; Sabiha Essack; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fever; acute febrile illness; fever; infectious disease; diagnostics; c-reactive protein; antibiotics; antibiotic resistance; Infektionssjukdomar; Infectious Diseases;

    Abstract :     Aim: This thesis examined the causes of acute febrile illness (AFI), the current use of antibiotics and diagnostics, and evaluated the diagnostic accuracy of C-Reactive Protein (CRP) to differentiate bacterial from non-bacterial causes of AFI in children and adult outpatients at R.D. Gardi Medical College hospital, in Ujjain, India. READ MORE

  7. 10. From Penicillin Binding Proteins to Community Interventions : Mathematical and Statistical Models Related to Antibiotic Resistance

    Author : Patricia Geli Rolfhamre; Åke Svensson; Mikael Andersson; Dan I. Andersson; Karl Ekdahl; Bruce R. Levin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistance; mathematical modeling; pharmacokinetics; pharmacodynamics; penicillin binding protein; postantibiotic effect; reversibility; selection; community intervention; Mathematical statistics; Matematisk statistik; matematisk statistik; Mathematical Statistics;

    Abstract : Antibiotic resistance has become a major public health concern and mathematical models are important analytical tools for the understanding, evaluation and prediction of the resistance problem and related control strategies.The risk of emerging antibiotic resistance and selection has rarely been a concern in the design of antibiotic drug dosing regimens. READ MORE