Search for dissertations about: "antidiabetic drugs thesis"

Showing result 1 - 5 of 16 swedish dissertations containing the words antidiabetic drugs thesis.

  2. 1. A fishing expedition for antidiabetic drugs : identifying new avenues to stimulate beta-cell regeneration

    Author : Christos Karampelias; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : All types of diabetes are characterized by loss of the insulin-producing β-cells that reside in the pancreas. While current treatments can manage the disease, there is still no cure available. Understanding and promoting endogenous β-cell regeneration is an attractive approach that can lead to an eventual cure for diabetes. READ MORE

  4. 2. Assessment of anti-diabetic effect of Vietnamese herbal drugs

    Author : Nguyen Khanh Hoa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : G-protein; type 2 diabetes; phanoside; antidiabetic plant; hypoglycemic agent; insulin secretion; pancreatic islets; Gynostemma pentaphyllum; Anemarrhena asphodeloides; Angiopteris evecta;

    Abstract : The prevalence of type 2 diabetes mellitus is increasing in Vietnam as well as in other developing countries (China, Indian subcontinent, and Africa). Searching for hypoglycemic agents with origin from domestic herbals was considered as a useful way to find novel therapy of the disease. After treatment i.p. READ MORE

  5. 3. Diabetes in primary care : quality of life, metabolic control, drugs and socioeconomic factors

    Author : Per Wändell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : diabetes mellitus; quality of life; socioeconomic factors; cross-sectional survey; Sweden; primary health care; disability pension; psychic symptoms; drug utilisation antidiabetic drugs; cardiovascular agents; lipid-lowering drugs;

    Abstract : Diabetes is one of the most common chronic diseases affecting the Swedish population, with a prevalence of 3-4%. Most diabetic patients receive their care in the primary health care service. READ MORE

  6. 4. Platelet function in diabetes mellitus : relationships to hyperglycaemia, antidiabetic treatment and microangiopathy

    Author : Marianne Yngen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Diabetes mellitus; platelet function; P-selectin; leukocyte-platelet cross-talk; endothelium; inflammation; coagulation; hyperglycaemia; metabolic control; microvascular complications; percutaneous coronary intervention.;

    Abstract : Diabetes mellitus is associated with accelerated atherosclerosis and increased morbidity and mortality in micro-and macrovascular complications. The metabolic derangements that accompany diabetes can adversely influence platelets and vascular endothelial function, which may contribute to the pathogenesis of diabetic angiopathy. READ MORE

  7. 5. Prevention of Pancreatic β-Cell Failure in Type 2 Diabetes. By Targeting a Mitochondrial Voltage Gated Channel 1 and a Novel class of GPCRs

    Author : Israa Mohammed; Diabetes - öpatofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : It has been long known that hyperglycaemia-induced β-cell dysfunction precipitates type 2 diabetes (T2D) in insulin-resistant obesity, although the underlying mechanisms are still poorly defined. The few frequently used antidiabetic drugs on the market have still not satisfactorily demonstrated any long-lasting improvements of β-cell function and prevention of the disease. READ MORE