Search for dissertations about: "antipsychotic activity in pharmacology thesis"

Found 3 swedish dissertations containing the words antipsychotic activity in pharmacology thesis.

  2. 1. Therapeutic Drug Monitoring in Psychiatry : Some aspects of utility in clinical practice and research

    Author : Maria Dolores Chermá Yeste; Finn Bengtsson; Johan Ahlner; Ylva Böttiger; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TDM; psychoactive drug; pharmacokinetics; pharmacogenetics; naturalistic; elderly; child; Clinical pharmacology; Klinisk farmakologi;

    Abstract : Background and objectives: Several new psychoactive drugs for the treatment of psychiatric disorders have been introduced onto the market since the late 1980s. Basic aspects of pharmacodynamics and pharmacokinetics (PK) are investigated before approval for general prescription. READ MORE

  4. 2. Dopaminergic stabilizers for the treatment of schizophrenia. Rat studies focusing on negative symptoms and mechanisms of action

    Author : Johan P. Rung; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ACR16; dopaminergic stabilizers; -MK-801; motor activity; negative symptoms; - -OSU6162; prolactin; rat; schizophrenia; social withdrawal;

    Abstract : Schizophrenia is a severe mental disorder manifested by positive, negative and cognitive symptoms. Current antipsychotic drugs have poor effects on negative and cognitive symptoms, thus necessitating the development of new antipsychotic treatments. Dopaminergic stabilizers constitute a novel concept for the treatment of schizophrenia. READ MORE

  5. 3. Regulation of monoaminergic functions by GPCRs with a special emphasis on mental and movement disorders

    Author : Ioannis Mantas; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Dysfunction of the brain’s monoaminergic system has been implicated in many human neurological and psychiatric disorders, such as Parkinson’s disease (PD), major depressive disorder (MDD) and schizophrenia. The monoamines that are most dysregulated in these diseases, are dopamine and serotonin. READ MORE