Search for dissertations about: "antiretroviral drugs"

Showing result 1 - 5 of 28 swedish dissertations containing the words antiretroviral drugs.

  1. 1. Development and Validation of Bioanalytical Methods : Application to Melatonin and Selected Anti-Infective Drugs

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Susanne Römsing; Uppsala universitet.; Högskolan Dalarna.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; Analytical Chemistry; Analytisk kemi; african trypanosomiasis; melatonin; malaria; antiretroviral drugs; lumefantrine; tafenoquine; lamivudine; nevirapine; zidovudine; sampling paper; dried blood spots; capillary blood; antimalarial drugs; solid-phase extraction; liquid chromatography;

    Abstract : This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. READ MORE

  2. 2. Antiretroviral treatment of HIV-1 in the central nervous system

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Aylin Yilmaz; Göteborgs universitet.; University of Gothenburg.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN; MEDICINE; HIV-1; cerebrospinal fluid; antiretroviral treatment; lopinavir; saquinavir; nelfinavir; neopterin; beta-2-microglobulin; HIV-1 RNA; IgG index; blood-brain barrier; albumin ratio; ultra-ultra sensitive PCR;

    Abstract : HIV-1 invades the central nervous system (CNS) early in the infectious course. It establishes a chronic progressive infection, and triggers an intrathecal immune response. If left untreated, a majority of patients will develop neurological complications, caused by opportunistic pathogens or HIV-1 itself. READ MORE

  3. 3. Short modified peptides and their metabolites inhibit HIV replication

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Elin Andersson; Göteborgs universitet.; University of Gothenburg.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN; MEDICINE; HIV-1; AIDS; GPG-NH2; G-NH2; antiretroviral drugs; Dipeptidyl peptidase IV; CD26; prodrug;

    Abstract : Several drugs inhibiting the replication of HIV-1, the causative agent of AIDS, are available today. However, HIV-1 treatment is hampered by side effects, poor adherence and development of resistance. READ MORE

  4. 4. Incidence, predictors and biomarkers for antiretroviral and/or anti-tuberculosis drugs induced liver injury

    University dissertation from Stockholm : Karolinska Institutet, Dept of Laboratory Medicine

    Author : Getnet Yimer Ali; Karolinska Institutet.; Karolinska Institutet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Anti-tuberculosis and/or antiretroviral drugs induced liver injury (DILI) is a major challenge when managing TB and/or HIV patients. The aims of this thesis were to identify incidence, risk factors, and management of DILI among 4 different treatment groups namely; HIV positive individuals with no TB co-infection and had a CD4 count of < 200 cells/μl (taking ARV drugs alone = arm 1), TB-HIV co-infected patients with a CD4 count of < 200 cells/μl (taking both anti-TB and ARV drugs = arm 2), TB-HIV coinfected patients with a CD4 count of > 200 cells/μl (taking anti-TB alone = arm 3), HIV negative TB patients (taking anti-TB alone = arm 4). READ MORE

  5. 5. Studies on the clinical pharmacology of antiretroviral agents

    University dissertation from Stockholm : Karolinska Institutet, Department of Laboratory Medicine

    Author : Filip Josephson; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : This thesis begins with an account of the development of the antiretroviral treatment paradigm for HIV infection, focusing on the emergence of present day principles of antiretroviral therapy (e.g. READ MORE