Search for dissertations about: "antiretroviral therapy"

Showing result 1 - 5 of 53 swedish dissertations containing the words antiretroviral therapy.

  1. 1. HIV-1 infection of the central nervous system. Markers of pathogenesis and antiretroviral treatment effects

    Author : Sahra Abdulle; Göteborgs universitet.; University of Gothenburg.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN; MEDICINE; HIV-1; cerebrospinal fluid; antiretroviral therapy; neopterin; beta2-microglobulin; CSF HIV-1 RNA; blood-brain barrier; IgG index; HIV-related neurological diseases; AIDS Dementia Complex; neurofilament protein; HIV-1 genetic subtypes;

    Abstract : Human immunodeficiency virus type 1 (HIV-1) invades the central nervous system (CNS) early in the course of infection and either directly or through opportunistic infections causes a spectrum of neurological complications. The most severe manifestation of HIV-1 CNS infection is AIDS Dementia Complex (ADC), which occurs in approximately 20% of untreated patients with AIDS. READ MORE

  2. 2. Lost in Transition: Pre-antiretroviral Care and Delayed Initiation of Antiretroviral Therapy in Uganda

    University dissertation from Stockholm : Karolinska Institutet, Dept of Public Health Sciences

    Author : Muhamadi Lubega; Karolinska Institutet.; Karolinska Institutet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; counselling;

    Abstract : Background: Comprehensive HIV care aims at providing care and support, from HIV counselling and testing, through pre-antiretroviral (pre-ARV) care to antiretroviral therapy (ART). However, many people living with HIV (PLHIV) do not start treatment or are lost to follow-up during pre-ARV care, and subsequently initiate ART very late, with a high risk of HIV/AIDS-related mortality. READ MORE

  3. 3. HIV Persistence and Viral Reservoirs

    University dissertation from Stockholm : Karolinska Institutet, Dept of Public Health Sciences

    Author : Arvid Edén; Göteborgs universitet.; University of Gothenburg.; [2010]
    Keywords : HIV-1; antiretroviral therapy; latency; cerebrospinal fluid; central nervous system; efavirenz; lopinavir; atazanavir; neopterin; viral decay;

    Abstract : Although antiretroviral therapy (ART) can effectively inhibit replication of human immunodeficiency virus type 1 (HIV-1), the virus is able to persist in cellular and anatomical viral reservoirs. Latently infected resting memory CD4+ T-cells are an important cellular reservoir, and the central nervous system (CNS) an important anatomical reservoir for HIV-1 infection. READ MORE

  4. 4. On HIV-1 infection in the central nervous system

    University dissertation from Stockholm : Karolinska Institutet, Dept of Public Health Sciences

    Author : Åsa Mellgren; Göteborgs universitet.; University of Gothenburg.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN; MEDICINE; HIV-1; antiretroviral therapy; cerebrospinal fluid; neurofilament protein; AIDS dementia complex; neuropsychological test;

    Abstract : HIV-1 (hereafter referred to as HIV) is a neurotropic virus that invades the central nervous system (CNS). The CNS is then susceptible to an acute infection and later to CNS opportunistic diseases and AIDS dementia complex (ADC). HIV does not infect the neurons, and neuropathogenesis is largely mediated by the immune system. READ MORE

  5. 5. Applied Population Pharmacokinetic/ Pharmacodynamic Modeling of Antiretroviral and Antimalarial Drug Therapy

    University dissertation from Stockholm : Karolinska Institutet, Dept of Public Health Sciences

    Author : Daniel Röshammar; Göteborgs universitet.; University of Gothenburg.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN; MEDICINE; HIV; malaria; pharmacokinetics; pharmacodynamics; pharmacometrics; NONMEM;

    Abstract : HIV/AIDS and malaria are two major global infectious diseases. Although better drugs against these conditions are becoming more available, dosages may not always be optimal with respect to effectiveness, safety, cost or convenience of administration. READ MORE