Search for dissertations about: "antiretroviral therapy"

Showing result 1 - 5 of 22 swedish dissertations containing the words antiretroviral therapy.

  1. 1. HIV-1 infection of the central nervous system. Markers of pathogenesis and antiretroviral treatment effects

    Author : Sahra Abdulle; Göteborgs universitet.; University of Gothenburg.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN; MEDICINE; HIV-1; cerebrospinal fluid; antiretroviral therapy; neopterin; beta2-microglobulin; CSF HIV-1 RNA; blood-brain barrier; IgG index; HIV-related neurological diseases; AIDS Dementia Complex; neurofilament protein; HIV-1 genetic subtypes;

    Abstract : Human immunodeficiency virus type 1 (HIV-1) invades the central nervous system (CNS) early in the course of infection and either directly or through opportunistic infections causes a spectrum of neurological complications. The most severe manifestation of HIV-1 CNS infection is AIDS Dementia Complex (ADC), which occurs in approximately 20% of untreated patients with AIDS. READ MORE

  2. 2. HIV Persistence and Viral Reservoirs

    Author : Arvid Edén; Göteborgs universitet.; University of Gothenburg.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; antiretroviral therapy; latency; cerebrospinal fluid; central nervous system; efavirenz; lopinavir; atazanavir; neopterin; viral decay;

    Abstract : Although antiretroviral therapy (ART) can effectively inhibit replication of human immunodeficiency virus type 1 (HIV-1), the virus is able to persist in cellular and anatomical viral reservoirs. Latently infected resting memory CD4+ T-cells are an important cellular reservoir, and the central nervous system (CNS) an important anatomical reservoir for HIV-1 infection. READ MORE

  3. 3. Pharmacometric Models to Improve Treatment of Tuberculosis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Elin M Svensson; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; pharmacodynamics; population approach; nonlinear mixed-effects models; multidrug-resistant tuberculosis; bedaquiline; antiretroviral; drug-drug interactions; time-to-event; albumin; Klinisk farmakologi; Clinical Pharmacology;

    Abstract : Tuberculosis (TB) is the world’s most deadly infectious disease and causes enormous public health problems. The comorbidity with HIV and the rise of multidrug-resistant TB strains impede successful therapy through drug-drug interactions and the lack of efficient second-line treatments. READ MORE

  4. 4. On HIV-1 infection in the central nervous system

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Åsa Mellgren; Göteborgs universitet.; University of Gothenburg.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN; MEDICINE; HIV-1; antiretroviral therapy; cerebrospinal fluid; neurofilament protein; AIDS dementia complex; neuropsychological test;

    Abstract : HIV-1 (hereafter referred to as HIV) is a neurotropic virus that invades the central nervous system (CNS). The CNS is then susceptible to an acute infection and later to CNS opportunistic diseases and AIDS dementia complex (ADC). HIV does not infect the neurons, and neuropathogenesis is largely mediated by the immune system. READ MORE

  5. 5. Who died, where, when and why? an investigation of HIV-related mortality in rural South Africa

    University dissertation from Umeå : Umeå University

    Author : Paul Mee; Umeå universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV; AIDS; Mortality; Determinants; Risk Factor; Spatial Epidemiology; Structural Determinant; Antiretroviral Therapy; Healthcare Access; South Africa; Sub-Saharan Africa; Traditional Medical Practitioner; Traditional Medicine; Tuberculosis; Health and Demographic Surveillance System; Global Health; Population Health; Epidemiology; epidemiologi; Epidemiology;

    Abstract : BackgroundSouth Africa has experienced the most severe consequences of the HIV/AIDS pandemic. Every community has been affected in some way, many experiencing huge increases in mortality,particularly before antiretroviral therapies (ART) were readily available. READ MORE