Search for dissertations about: "antiretroviral therapy"

Showing result 16 - 20 of 107 swedish dissertations containing the words antiretroviral therapy.

  2. 16. Preclinical studies of ribozyme-mediated gene therapy for HIV-1

    Author : Catharina Maijgren Steffensson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : AIDS; antiretroviral; cis-cleavage; gene therapy; HAART; hairpin; hammerhead; HIV-1; in vitro; in vivo; ribozyme; RNA;

    Abstract : Approximately 40 million people are infected with HIV-1 and AIDS is the number one cause of death in Africa as well as, the fourth leading cause of death globally. Patients in developed countries generally receive highly active antiretroviral therapy (HAART), even though the drugs are expensive and sometimes cause side-effects and treatment failure. READ MORE

  4. 17. m-Health for antiretroviral treatment support : evidence from India

    Author : Rashmi Josephine Rodrigues; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: With antiretroviral therapy (ART) HIV infection is now managed like a chronic disease rather than as a fatal disease. Adherence to ART is essential for treatment success. However the high levels of adherence that are necessary and the multifactorial nature of adherence, make adherence to ART a challenge. READ MORE

  5. 18. The battleground of two Infections and a cancer: Human Papilloma Virus, premalignant lesions of the cervix and their interaction with Human Immunodeficiency Virus in southwestern Nigeria

    Author : Oliver Ezechi; Socialmedicin och global hälsa; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antiretroviral drugs; Human papilloma virus; cervical cancer; HIV AIDS; pre-cancerous lesions; Nigeria;

    Abstract : Background: The highest numbers of HIV-infected women are in sub- Saharan Africa, where the natural progression of HIV disease in the absence of treatment results in death before the onset of invasive cervical cancer. With improved access to treatment, several studies outside West Africa demonstrated an increased risk of pre-invasive cervical lesions among HIV-infected women and the positive impact of treatment on the outcome. READ MORE

  6. 19. Assays for monitoring HIV therapy in low-middle income countries

    Author : Eva Agneskog; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The purpose of this thesis was to develop and/or evaluate assays for HIV viral load (VL) monitoring and HIV drug resistance testing of potential importance for research studies and clinical care in low- and middle income countries (LMICs). This was achieved using reverse transcriptase based (RT) assays and blood samples from Vietnamese and Swedish HIV-1 infected patients. READ MORE

  7. 20. Evolution of HIV-1 coreceptor use in relation to pathogenesis

    Author : Ingrid Karlsson; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; RANTES; higly active antiretroviral therapy; pathogenesis; lymphoid tissue; cehmokine receptor; biological phenotype; coreceptor; HIV-1; evolution;

    Abstract : HIV-1 uses the coreceptors CCR5 and/or CXCR4 in addition to CD4 to enter the host cell. CCR5-using HIV-1 (R5 phenotype) appears to transmit infection and usually dominates the early stages of disease. READ MORE