Search for dissertations about: "antiretroviral treatment"

Showing result 1 - 5 of 25 swedish dissertations containing the words antiretroviral treatment.

  1. 1. Antiretroviral treatment of HIV-1 in the central nervous system

    Author : Aylin Yilmaz; Göteborgs universitet.; Gothenburg University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; cerebrospinal fluid; antiretroviral treatment; lopinavir; saquinavir; nelfinavir; neopterin; beta-2-microglobulin; HIV-1 RNA; IgG index; blood-brain barrier; albumin ratio; ultra-ultra sensitive PCR;

    Abstract : HIV-1 invades the central nervous system (CNS) early in the infectious course. It establishes a chronic progressive infection, and triggers an intrathecal immune response. If left untreated, a majority of patients will develop neurological complications, caused by opportunistic pathogens or HIV-1 itself. READ MORE

  2. 2. Pharmacometric Models to Improve Treatment of Tuberculosis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Elin M Svensson; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; pharmacodynamics; population approach; nonlinear mixed-effects models; multidrug-resistant tuberculosis; bedaquiline; antiretroviral; drug-drug interactions; time-to-event; albumin; Klinisk farmakologi; Clinical Pharmacology;

    Abstract : Tuberculosis (TB) is the world’s most deadly infectious disease and causes enormous public health problems. The comorbidity with HIV and the rise of multidrug-resistant TB strains impede successful therapy through drug-drug interactions and the lack of efficient second-line treatments. READ MORE

  3. 3. Adherence and Readiness to Antiretroviral Treatment

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Björn Södergård; Uppsala universitet.; [2006]
    Keywords : Community pharmacy services; Adherence; Readiness; HIV; Pharmacy; Samhällsfarmaci;

    Abstract : Antiretroviral therapy places extraordinarily high demands on adherence, since non-adherence affects both individuals and society due to the spread of resistant viral strains. The aims of the thesis were to investigate the prevalence of adherence in Swedish HIV-infected patients, changes in adherence over time, and factors associated with adherence, including patients’ readiness to adhere. READ MORE

  4. 4. HIV-1 infection of the central nervous system. Markers of pathogenesis and antiretroviral treatment effects

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sahra Abdulle; Göteborgs universitet.; Gothenburg University.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; cerebrospinal fluid; antiretroviral therapy; neopterin; beta2-microglobulin; CSF HIV-1 RNA; blood-brain barrier; IgG index; HIV-related neurological diseases; AIDS Dementia Complex; neurofilament protein; HIV-1 genetic subtypes;

    Abstract : Human immunodeficiency virus type 1 (HIV-1) invades the central nervous system (CNS) early in the course of infection and either directly or through opportunistic infections causes a spectrum of neurological complications. The most severe manifestation of HIV-1 CNS infection is AIDS Dementia Complex (ADC), which occurs in approximately 20% of untreated patients with AIDS. READ MORE

  5. 5. Development and Validation of Bioanalytical Methods Application to Melatonin and Selected Anti-Infective Drugs

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Susanne Römsing; Uppsala universitet.; Högskolan Dalarna.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; Analytical Chemistry; Analytisk kemi; african trypanosomiasis; melatonin; malaria; antiretroviral drugs; lumefantrine; tafenoquine; lamivudine; nevirapine; zidovudine; sampling paper; dried blood spots; capillary blood; antimalarial drugs; solid-phase extraction; liquid chromatography;

    Abstract : This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. READ MORE