Search for dissertations about: "antisense"

Showing result 1 - 5 of 119 swedish dissertations containing the word antisense.

  1. 1. Antisense technology and bone resorption

    University dissertation from Chalmers University of Technology

    Author : Marie Suzanne Westberg; Chalmers tekniska högskola.; Chalmers University of Technology.; [1996]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antisense DNA; bone resorption; ostoclast; vacuolar H -ATPase; carbonic anhydrase II;

    Abstract : .... READ MORE

  2. 2. Functional characterization of the small antisense RNA MicA in Escherichia coli

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Klas Ifeanyi Udekwu; Uppsala universitet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small RNA; antisense; outer membrane; Hfq-dependence; RNase III; LuxS; Quorum sensing; MEDICINE Microbiology; immunology; infectious diseases Microbiology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi; mikrobiologi; Microbiology;

    Abstract : The Escherichia coli small RNA (sRNA) MicA was identified recently in a genomewide search for sRNAs. It is encoded between the genes gshA and luxS in E. coli and its close relatives. The function of sRNAs in bacteria is generally believed to be in maintenance of homeostasis via stress-induced modulation of gene expression. READ MORE

  3. 3. Making Sense of Antisense

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Johan Reimegård; Uppsala universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; sRNA; miRNA; RNA; target prediction; SOLiD siRNA; E.coli; D.discoideum; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi; Bioinformatik; Bioinformatics; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : RNA is a highly versatile molecule with functions that span from being a messenger in the transfer from DNA to protein, a catalytic molecule important for key processes in the cell to a regulator of gene expression. The post-genomic era and the use of new techniques to sequence RNAs have dramatically increased the number of regulatory RNAs during the last decade. READ MORE

  4. 4. Conformationally Constrained Nucleosides Design, Synthesis, and Biochemical Evaluation of Modified Antisense Oligonucleotides

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Oommen P. Varghese; Uppsala universitet.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; chemically modified oligonucleotides; azetidine; aza-ENA-T; cyanomethylene locked; free energy of activation; diaxial interactions; chair conformation; stable duplex; human serum; snake venom phosphodiesterase; antisense agents; RNase H; Organisk kemi; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi;

    Abstract : This thesis is concerned with synthesis, structure and biochemical analysis of chemically modified oligonucleotides with potential therapeutic applications. The three types of chemical modifications described here are: (a) A North-East locked 1',2'-azetidine nucleoside (b) A North locked 2',4'-cyanomethylene bridged nucleoside and (c) A 2',4'-aza-ENA-T nucleoside. READ MORE

  5. 5. Dissecting the photosystem II light-harvesting antenna

    University dissertation from Umeå : Fysiologisk botanik

    Author : Jenny Andersson; Umeå universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plant physiology; antisense; Arabidopsis thaliana; chlorophyll; carotenoid; feedback de-excitation; fitness; LHC; NPQ; photosynthesis; state transitions; xanthophyll; Växtfysiologi; NATURAL SCIENCES Biology Organism biology Plant physiology; NATURVETENSKAP Biologi Organismbiologi Växtfysiologi; Physiological Botany; fysiologisk botanik;

    Abstract : In photosynthesis, sunlight is converted into chemical energy that is stored mainly as carbohydrates and supplies basically all life on Earth with energy.In order to efficiently absorb the light energy, plants have developed the outer light harvesting antenna, which is composed of ten different protein subunits (LHC) that bind chlorophyll a and b as well as different carotenoids. READ MORE