Search for dissertations about: "apoptosis"

Showing result 16 - 20 of 1200 swedish dissertations containing the word apoptosis.

2. 16. Molecular Studies of Mast Cell Migration and Apoptosis : Two Ways of Regulating Mast Cell Numbers at Sites of Inflammation

   Author : Jessica Alfredsson; Gunnar Nilsson; Hans-Uwe Simon; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; mast cell; SCF; IL-3; FcεRI; migration; apoptosis; Bim; Bcl-2; Bcl-XL; Akt; FOXO; MAPK; Patologi; Pathology; Patologi;

   Abstract : Upon activation mast cells release numerous proinflammatory mediators. With this feature, mast cells play an important role in host defense against pathogens, and are involved in tissue remodeling and wound healing. However, in cases of excessive inflammation the effects of mast cells are detrimental. READ MORE

4. 17. Transmethylation, Polyamines and Apoptosis in Amyotrophic Lateral Sclerosis

   Author : Titti Ekegren; Håkan Askmark; Cecilia Gomes-Trolin; Sten-Magnus Aquilonius; Christopher Fowler; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; amyotrophic lateral sclerosis; neurodegeneration; transmethylation; polyamine; apoptosis; Neurovetenskap; Neurology; Neurologi;

   Abstract : Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive disorder characterized by degeneration of motor neurons in the cortex, brainstem and spinal cord. The patients usually die within 3-5 years after onset. The full etiology of ALS is unknown and many hypotheses have been proposed to explain the neurodegeneration. READ MORE

5. 18. Novel Interactors of X-linked Inhibitor of Apoptosis Protein : Expression and Effects on Tumor Cell Death

   Author : Håkan Steen; Dan Lindholm; Bertrand Joseph; Uppsala universitet; []
   Keywords : Neurobiology; XIAP; tumor cell death; apoptosis; caspases; basic helix-loop-helix protein; Neurobiologi;

   Abstract : Programmed cell death, or apoptosis, has during the last decade received a lot of attention due to its involvement in a large number of pathological conditions. Since death is always irreversible, it is important for cells to fully control the initiation and execution of this process. READ MORE

6. 19. Studies on the Role of Apoptosis in Kidney Diseases

   Author : Linnéa Nilsson; Hjalmar Brismar; Anita Aperia; Lena Scott; Fredrik Palm; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; diabetic kidney disease; hyperglycemia; mesangial cells; microscopy; ouabain; podocytes; proximal tubule cells; RNA-seq; SGLT; Apoptos; diabetisk njursjukdom; hyperglykemi; mesangiala celler; mikroskopi; ouabain; podocyter; proximala tubuli celler; RNA-seq; SGLT; Biological Physics; Biologisk fysik;

   Abstract : Apoptosis is one of the most common types of cell death. Under physiological conditions, it plays an essential role in removal of damaged and potentially harmful cells. Excessive apoptosis has however been linked to a number of diseases including proteinuric kidney disease and DKD, and is believed to enhance the disease progression. READ MORE

7. 20. Structural studies of proteins in apoptosis and lipid signaling

   Author : Maria Dolores Herman Moreno; Pär Nordlund; Markus Gruetter; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; proteins; crystal structure; apoptosis; cancer; CoFi-Blot; kinases; lipid signaling; Structural biology; Strukturbiologi; Structural Biology; strukturbiologi;

   Abstract : Signaling pathways control the fate of the cell. For example, they promote cell survival or commit the cell to death (apoptosis) in response to cell injury or developmental stimuli, decisions, which are vital for the proper development and functioning of metazoan. READ MORE