Search for dissertations about: "arsenic trioxide"

Showing result 1 - 5 of 6 swedish dissertations containing the words arsenic trioxide.

  1. 1. Effects of arsenic trioxide and hypoxia in multidrug-resistant neuroblastoma

    University dissertation from Lund University, Faculty of Medicine

    Author : Jenny Karlsson; Lunds universitet.; Lund University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; neuroblastoma; multidrug resistance; hypoxia; glucose-deficiency; cell death; Bax; Apoptosis; arsenic trioxide;

    Abstract : Neuroblastoma is a childhood tumour derived from the sympathetic nervous system. Although most children with neuroblastoma initially respond to treatment, approximately 50% of these patients relapse with multidrug-resistant tumours. Arsenic trioxide (As2O3) has been used for centuries to treat different clinical disorders including malignancies. READ MORE

  2. 2. Hypoxic Adaptation and Arsenic Trioxide Treatment in Small Cell Lung Carcinoma

    University dissertation from Molecular Medicine

    Author : Matilda Thorén; Lunds universitet.; Lund University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small cell lung carcinoma; arsenic trioxide; hypoxia; hypoxia-inducible factors; survival; proliferation; glycolysis; glutamine metabolism; MYC;

    Abstract : Popular Abstract in Swedish Cancer är ett samlingsnamn för en grupp av sjukdomar som karakteriseras av att cellerna delar sig okontrollerat, till skillnad mot kroppens friska celler. Det leder till att en tumör kan bildas och cellerna kan därifrån sprida sig till andra delar av kroppen och ge upphov till dottertumörer, även kallade metastaser. READ MORE

  3. 3. Approaches to Treatment of Children with Advanced Neuroblastoma

    University dissertation from Ingrid Øra, Div. of Pediatric Oncology and Hematology, University Hospital Lund, 221 85 Lund, Sweden

    Author : Ingrid Øra; Lunds universitet.; Lund University.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; drug resistance; hypoxia; apoptosis; arsenic trioxide; treatment; diagnosis; neuroblastoma; sympathetic nervous system; Pediatri; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : Children with advanced neuroblastoma are at high risk for relapse of multidrug resistant disease, despite initial response to intensive multimodality treatment. Neuroblastomas have similarities with immature neuroblasts seen during embryonic development of the sympathetic nervous system (the origin of these tumors). READ MORE

  4. 4. Clinical and Experimental Studies in Chronic Myeloid Leukemia Studies of Treatment Outcome, In Vitro Cellular Drug Resistance and Gene Expression

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ulla Olsson-Strömberg; Uppsala universitet.; [2007]
    Keywords : Medicine; chronic myeloid leukemia; adult; stem cell transplantation; mobilization of Ph-negative stem cells; in vitro assay; imatinib; gene expression; Medicin;

    Abstract : The aims of the studies described in the thesis were to investigate different treatment strategies in chronic myeloid leukemia (CML) patients. Furthermore, activity of imatinib was investigated by in vitro cytotoxicity assay, and the gene expression pattern in interferon treated patients. READ MORE

  5. 5. Lipid mediators in the prevention and therapy of neuroblastoma

    University dissertation from Stockholm : Karolinska Institutet, Department of Women's and Children's Health

    Author : Helena Gleissman; Karolinska Institutet.; Karolinska Institutet.; [2009]

    Abstract : Neuroblastoma is a cancer of the nervous system that mainly affects infants and young children. It is the most common solid extracranial tumor of childhood, and accounts for almost 10% of all childhood cancer deaths. READ MORE