Search for dissertations about: "ascites"

Showing result 1 - 5 of 30 swedish dissertations containing the word ascites.

  2. 1. Cancer Evolution under Chemotherapy Treatment

    Author : Kaname Uno; Cancercellers evolution; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; Wilms tumor; chemotherapy resistance; ascites; spheroids; diffuse anaplasia;

    Abstract : Background: Chemotherapy resistance is a critical issue in oncology, being responsible for the majority of deaths in modern cancer care. My PhD work has focused on two cancer types where such drug resistance is a major clinical issue: epithelial ovarian cancer (EOC) and Wilms tumor (WT). READ MORE

  4. 2. The release of histone proteins from cells via extracellular vesicles

    Author : Uma Muthukrishnan; Jonathan Gilthorpe; Miles Trupp; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histone; extracellular vesicles; exosomes; extracellular histones extracellular DNA; cellular stress; proteomics; ESCRT complex; Lrrn1; mid-hindbrain organizer; ovarian cancer; ascites;

    Abstract : Histones are chromatin-associated proteins localized to the nucleus. However, extracellular histones are present in biofluids from healthy individuals and become elevated under disease conditions, such as neurodegeneration and cancer. READ MORE

  5. 3. Studies on a polypeptide inhibiting cell growth obtained from human ascites tumour fluid

    Author : Bo E. G. Holmberg; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : .... READ MORE

  6. 4. Demonstration and characterization of ecto-sialyltransferase in surface membranes of intact Ehrlich ascites tumour cells

    Author : Erik Cervén; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  7. 5. p53 inactivation by point mutations and splice site mutations in human and mouse tumors

    Author : Kristinn P Magnússon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : p53; Burkitt Iymphoma; apoptosis; alternative splicing; mutation; ascites;

    Abstract : The p53 tumor suppressor gene is frequently mutated in human tumors. p53 induces cell cycle arrest and/or apoptosis in response to cellular stress, such as DNA damage, hypoxia and certain activated oncogenes like c-myc. The status of p53 in Burkitt's Iymphoma (BL) cell lines was investigated. The majority of BL lines expressed mutated p53 protein. READ MORE