Search for dissertations about: "astrogliosis"

Showing result 1 - 5 of 23 swedish dissertations containing the word astrogliosis.

  1. 1. NEURAL STEM/PROGENITOR CELLS IN THE POST-ISCHEMIC ENVIRONMENT: Proliferation, Differentiation and Neuroprotection

    Author : Jonas Faijerson; Göteborgs universitet; []
    Keywords : neural stem cells; neural progenitor cells; stroke; ischemia; reactive astrocytes; astrogliosis; proliferation; differentiation; neurogenesis; excitotoxicity; transfection; neuroprotection;

    Abstract : Stroke is one of the leading causes of chronic disability and death in the Western world. Today, no treatment can repair the cellular loss associated with an ischemic lesion. READ MORE

  2. 2. Neuroprotective Effect of Genistein : Studies in Rat Models of Parkinson’s and Alzheimer’s Disease

    Author : Maryam Bagheri; Simin Mohseni; David Engblom; Jan Marcusson; Mark J. West; Linköpings universitet; []
    Keywords : ;

    Abstract : Parkinson’s disease (PD) and Alzheimer’s disease (AD) are neurodegenerative disorders that mainly affect the elderly population. It is believed that oxidative stress is involved in development of both these diseases and that estrogen deficiency is a risk factor for development of AD. READ MORE

  3. 3. Tau pathology in Alzheimer's disease and other dementias : translational approach from in vitro autoradiography to in vivo PET imaging

    Author : Mona-Lisa Malarte; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tauopathies, including Alzheimer's disease (AD), corticobasal degeneration (CBD), and progressive supranuclear palsy (PSP), are complex neurodegenerative disorders characterized by the pathological accumulation of tau proteins in the brain. These often overlapping disorders, with intricate pathologies and growing prevalence, lack definitive treatments, highlighting the necessity for advanced research. READ MORE

  4. 4. Inflammation and neurodegeneration in mouse nervous system : experimental application

    Author : Rui-Sheng Duan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Experimental autoimmune neuritis (EAN) is a CD4+ T cell mediated inflammatory autoimmune disease of peripheral nervous system (PNS) and shares many of clinical, immunological, electrophysiological and morphological characteristics of human Guillain-Barré syndrome (GBS). Hence, EAN is considered to represent a useful model for studying the pathogenesis and therapy of human GBS. READ MORE

  5. 5. Blood and CSF biomarkers for investigation of the immunopathogenesis of relapse in Multiple Sclerosis

    Author : Clas Malmeström; Göteborgs universitet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). MS usually starts with a relapsing-remitting course (RRMS) that later converts into a secondary progressive phase (SPMS). While inflammation is considered predominating in RRMS, neurodegenerative processes are probably more important in SPMS. READ MORE