Search for dissertations about: "atrophy"

Showing result 1 - 5 of 251 swedish dissertations containing the word atrophy.

2. 1. Signaling factors related to atrophy and hypertrophy in denervated skeletal muscle

   Author : Ann-Kristin Fjällström; Sven Tågerud; Jan Henriksson; Linnéuniversitetet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrophy; Hypertrophy; Skeletal muscle; Denervation; Protein synthesis; Protein degradation; Biomedical Sciences; Biomedicinsk vetenskap;

   Abstract : The human body consists of about 40 % skeletal muscles which control the body’s movement, ability to stand up, force generation, locomotion, heat production and are also the body’s protein reservoir. Muscle mass is controlled by the relationship between protein synthesis and protein degradation. READ MORE

4. 2. Telomeres and the brain : an investigation into the relationships of leukocyte telomere length with functional and structural attributes of the brain

   Author : Mikael Wikgren; Karl-Fredrik Norrback; Rolf Adolfsson; Göran Roos; Thomas Karlsson; Brenda Penninx; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APOE; aging; atrophy; brain; cognition; cortisol; depression; hippocampus; HPA axis; MRI; stress; telomere length; white matter hyper-intensities.;

   Abstract : Telomeres are the outermost parts of linear chromosomes. They consist of tandemly repeated non-coding short nucleotide sequences (TTAGGG in all vertebrates), in humans spanning over the last 2 to 15 kilobase pairs of the chromosome. Due to the end-replication problem, telomeres shorten with each cellular division. READ MORE

5. 3. Gene and protein expression in denervated atrophic and hypertrophic skeletal muscle

   Author : Marlene Norrby; Sven Tågerud; Linnéuniversitetet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Skeletal muscle; Denervation; Hypertrophy; Atrophy; Gene expression; Protein expression; Protein phosphorylation; NIFK; Wnt; MK2; Akt signaling;

   Abstract : Following denervation skeletal muscles change their functional and structural properties. Some changes resemble conditions in developing muscles and may be important for reinnervation. Due to inactivity following denervation most skeletal muscles loose muscle mass and become atrophic. READ MORE

6. 4. INFLAMMATION AND PROSTATIC CARCINOGENESIS ? A MORPHOLOGICAL STUDY OF THE HUMAN PROSTATE

   Author : Wanzhong Wang; Göteborgs universitet; []
   Keywords : prostate; carcinogenesis; chronic inflammation; atrophy; morphology; immunohistochemistry;

   Abstract : ABSTRACT: Chronic inflammation has been suggested to be linked to cancers. Inflammatory infiltrates are often found in and around foci of prostatic atrophy. These foci, called proliferative inflammatory atrophy (PIA), are proposed as precursors of prostate cancer (PCa) or prostatic intraepithelial neoplasia (PIN). READ MORE

7. 5. Cellular and Molecular Mechanisms Underlying Acute Quadriplegic Myopathy : Studies in Experimental Animal Models and Intensive Care Unit Patients

   Author : Holly Norman; Lars Larsson; Thomas Sejersen; Uppsala universitet; []
   Keywords : Neurosciences; Acute Quadriplegic Myopathy; intensive care unit; atrophy; myosin heavy chain; actin; myosin binding proteins; nuclear transcription factors; mRNA; Neurovetenskap;

   Abstract : The combination of a severe systemic illness, corticosteroids, and neuromuscular blocking agents in patients on the mechanical ventilator often results in a condition known as Acute Quadriplegic Myopathy (AQM). While severe weakness of all spinal nerve innervated muscles is known to be a significant clinical characteristic of the disease, this symptom is typically not recognized until the disease has progressed to an advanced stage. READ MORE