Search for dissertations about: "bacteria recognition"

Showing result 1 - 5 of 107 swedish dissertations containing the words bacteria recognition.

  2. 1. Peptidoglycan Recognition Proteins : Major Regulators of Drosophila Immunity

    Author : Peter Mellroth; Håkan Steiner; Julien Royet; Stockholms universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Innate immunity; peptidoglycan recognition protein; PGRP; Toll; Imd; Drosophila immunity; Microbiology and immunology; Mikrobiologi och immunologi;

    Abstract : All eukaryotic organisms have an innate immune system characterized by germ-line encoded receptors and effector molecules, which mediate detection and clearance of microbes such as bacteria, fungi, and parasites. VertebrateDrosophila as a genetically tractable organism with a This thesis concerns the peptidoglycan recognition protein (PGRP) gene family in the fruit fly. READ MORE

  4. 2. Uncovering novel cell wall chemistries in gram negative bacteria : from development or dedicated peptidoglycan chemometric tools to functional genomics

    Author : Akbar Espaillat; Felipe Cava; Sun Nyunt Wai; Waldemar Vollmer; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bacteria; cell wall; peptidoglycan; peptidoglycan variations; D-amino acids; molekylärbiologi; Molecular Biology;

    Abstract : Bacteria are surrounded by an external cell wall whose main component is a polymeric net-like structure called the peptidoglycan (PG) or murein sacculus. PG plays crucial roles in bacterial physiology (eg morphogenesis, growth fitness and regulation of innate immunity). READ MORE

  5. 3. Interaction Between Drosophila melanogaster mbn-2 Cells and Bacteria

    Author : Karin Johansson; Kenneth Söderhäll; Lage Cerenius; Martin Bilej; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Drosophila; innate immunity; bacteria; host - pathogen interaction; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : Innate immunity relies on a repertoire of germline-encoded non-rearranging pattern recognition receptors that bind to invariant microbial surface molecules. This event initiates a number of signal transduction cascades that lead to humoral and cellular defense responses like synthesis of antimicrobial peptides, phagocytosis and coagulation – mechanisms that efficiently fight infectious microorganisms and have been evolutionary conserved to exist in parallel with the antibody-based adaptive immunity found in vertebrates. READ MORE

  6. 4. Peptidoglycan recognition proteins in Drosophila melanogaster

    Author : Thomas Werner; Dan Hultmark; Bruno Lemaitre; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Drosophila; PGRP; peptidoglycan; pattern recognition; imd; Relish; isoform; RNAi; mbn-2; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The fruit fly Drosophila melanogaster is an excellent model organism to study the innate immune response, because insects and mammals share conserved features regarding the recognition and destruction of microorganisms and Drosophila is easily accessible to genetic manipulation. In my present study, I identified a new family of pattern recognition molecules for bacterial peptidoglycan in Drosophila, the Peptidoglycan Recognition Proteins (PGRP). READ MORE

  7. 5. Mucus associated proteins and their functional role in the distal intestine

    Author : Joakim H. Bergström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestine; mucus; bacteria; MUC2; AGR2; FCGBP; ZG16;

    Abstract : The mammalian intestine, especially the large intestine, harbors complex societies of beneficial bacteria coexisting with the host. This is a mutualistic relationship, where the host provides nutrients and a favorable environment while the bacteria in return ferment indigestible polysaccharides to short chain fatty acids. READ MORE