Search for dissertations about: "beta-turn"
Found 2 swedish dissertations containing the word beta-turn.
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1. Synthesis of β-turn and pyridine based peptidomimetics
Abstract : Despite the unfavorable pharmacokinetic properties associated with peptides, they are still of great interest in drug development due to a multitude of interesting biological functions. The development of peptidomimetics strives to maintain or improve the biological activity of a peptide concurrently with removing the unwanted properties. READ MORE
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2. Studies towards ß-turn mimetics, synthesis of kedarosamine from threonine, and synthesis of glycopeptides from mucins and gp120
Abstract : The secondary structure of proteins is crucial for proper function of the protein in biological systems. Peptide T, an octapeptide from the envelope glycoprotein gp120 of the HIV virus, has previously been shown to be responsible for binding to the CD4 receptor on T helper/inducer lymphocytes. READ MORE