Search for dissertations about: "biglycan"

Showing result 1 - 5 of 23 swedish dissertations containing the word biglycan.

  1. 1. Collagen VI - Molecular Assembly and Interactions

    Author : Charlotte Wiberg; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical biology; extracellular matrix; glycosaminoglycan; proteoglycan; collagen; biglycan; decorin; Klinisk biologi;

    Abstract : The extracellular matrix plays an integral role in tissue remodeling and development and it defines the different mechanical properties of a variety of connective tissues. Its complexity in composition and the details in organization has only been partly elucidated. READ MORE

  2. 2. Biosynthesis of Dermatan Sulphate. Enzymatic mechanism and role of cytokines

    Author : Kerstin Tiedemann; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dermatan sulphate; 4-O-sulfotransferase; Co-polymeric structure; biglycan; decorin; Biochemistry; Biokemi; C5-epimerase; Metabolism;

    Abstract : Dermatan sulphate is a prominent feature of several different proteoglycans and occurs in almost every tissue of the body. It is an unbranched polymer containing the repeating disaccharide unit of N-acetylgalactosamine and D-glucuronic acid or L-iduronic acid. READ MORE

  3. 3. Biglycan as a modulator of fibrous connective tissue

    Author : Ellen Tufvesson; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biglycan decorin fibroblast interleukin-1beta migration proteoglycan structure tumour necrosis factor-alpha; Medicine human and vertebrates ; Medicin människa och djur ;

    Abstract : Fibrous connective tissue contains fibroblasts distributed in a complex network of extracellular matrix molecules, such as proteoglycans. The small proteoglycans biglycan and decorin are composed of a protein core substituted with two and one glycosaminoglycan (GAG) chain, respectively. READ MORE

  4. 4. Ultraviolet radiation and cornea

    Author : Alexander Podskochy; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cornea; UVR; keratocytes; apoptosis; Fas ligand; hyaluronan; biglycan; rabbit; wound healing.;

    Abstract : Background: Acute exposure of the mammalian eye to UVR results in development of photokeratitis after a period of a few hours. Chronic exposure to UVR is associated with an increased risk of several corneal disorders, including pterygium, climatic droplet keratopathy, and climatic proteoglycan stromal keratopathy. READ MORE

  5. 5. The role of leucine-rich repeat glycoproteins/proteoglycans in the assembly of collagen matrices

    Author : Liz Svensson; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; Skelett; decorin; Collagen; fibromodulin; extracellular matrix; lumican; collagen fibrillogenesis; Skeleton; rheumatology locomotion; muscle system; Biochemistry; Biokemi; Metabolism;

    Abstract : The properties of different connective tissues depend on the synthesis and assembly of macromolecular structures composed of collagen and other extracellular matrix components. Mechanisms modulating these events play important roles in the formation of a functional tissue. READ MORE