Search for dissertations about: "binol reactions"

Showing result 1 - 5 of 6 swedish dissertations containing the words binol reactions.

2. 1. METAL CARBONYL MEDIATED REACTIONS - APPLICATIONS IN THE SYNTHESIS OF POTENTIAL GALECTIN INHIBITORS

   Author : Nuria Parera Pera; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES;

   Abstract : AbstractThis work reports the development of an asymmetric version of the Nicholas reaction using monodentate phosphoramidites as ligands, which enables asymmetric synthesis from racemic starting material. In addition, we describe the application of metal carbonyl mediated reactions, such as the Pauson-Khand reaction (PKR) and reactions involving cationic iron carbonyl dienyl complexes, for the synthesis of potential galectin inhibitors, implicated in human inflammatory responses and various pathologies. READ MORE

4. 2. Catalytic Regio- and Stereoselective Reactions for the Synthesis of Allylic and Homoallylic Compounds

   Author : Rauful Alam; Kalman Szabo; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; palladium catalysis; C−H functionalization; boronic acid; allylboration; asymmetric catalysis; allylic; homoallylic; diastereoselective; enantioselective; organisk kemi; Organic Chemistry;

   Abstract : This thesis is focused on two main areas of organic synthesis, palladium-catalyzed functionalization of alkenes and allylic alcohols, as well as development of new allylboration reactions.We have developed a palladium-catalyzed selective allylic trifluoroacetoxylation reaction based on C−H functionalization. READ MORE

5. 3. Palladium-Catalyzed Synthesis and Transformations of Organometallic Compounds

   Author : Olov Wallner; Kálmán Szabó; Robin Bedford; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; palladium; Organic chemistry; Organisk kemi;

   Abstract : This thesis is focused on two important fields of palladium catalysis: the development of electrophilic allylic substitution reactions via bis-allylpalladium intermediates; and application of palladium pincer-complexes in the synthesis and transformations of organometallic compounds.Palladium-catalyzed electrophilic allylation of aldehyde and imine substrates could be achieved using readily available allyl chlorides and acetates by employing hexamethylditin or bis(pinacolato)diboron reagents. READ MORE

6. 4. Synthesis of chiral allyl and propargyl boronates by organocatalytic carbene insertion to carbon-boron bonds

   Author : Marie Deliaval; Kálmán Szabó; Fahmi Himo; Carlos Valdés; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; boron; asymmetric synthesis; organocatalysis; allylic compounds; allenols; Organic Chemistry; organisk kemi;

   Abstract : This thesis describes the development of a novel organocatalytic method for the synthesis of chiral allyl- and propargyl- organoboron compounds with high enantioselectivity. These organoboron species are versatile building blocks in asymmetric synthesis.We have developed a new efficient homologation method of alkenyl boronic acids. READ MORE

7. 5. Fine-tuning of the catalytic activity and selectivity of palladium pincer complexes

   Author : Juhanes Aydin; Stockholms universitet; []
   Keywords : ;

   Abstract : This thesis is focused on optimization of the catalytic properties of so-called pincer complexes. This work involved synthesis of a large variety of palladium pincer complexes, which were applied in various organic transformations. READ MORE