Search for dissertations about: "biofysik"

Showing result 1 - 5 of 676 swedish dissertations containing the word biofysik.

  1. 1. Biophysical studies of cell-penetrating peptides and of the RNR inhibitor Sml1

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Elsa Bárány-Wallje; Stockholms universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cell-penetrating peptides; transportan; bicelles; Sml1; TECHNOLOGY Engineering physics Biophysics; TEKNIKVETENSKAP Teknisk fysik Biofysik; Biophysics; biofysik;

    Abstract : Several short peptides, so called cell-penetrating peptides, have the capability to transport large hydrophilic cargos through the cell membrane. The objective is to use these peptides as drug carriers and thereby enhance the uptake of drugs into cells.Three different cell-penetrating peptides are characterized in this thesis. READ MORE

  2. 2. Structure and Dynamics of Membrane Associated Peptides

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Henrik Biverståhl; Stockholms universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TECHNOLOGY Engineering physics Biophysics; TEKNIKVETENSKAP Teknisk fysik Biofysik; Biophysics; biofysik;

    Abstract : The peptide-membrane interaction is a key element for many biological functions, from cell signaling to cell internalization. In this thesis the peptide-membrane interaction of six different peptides have been studied with respect to their structure, membrane location and dynamics with spectroscopic methods. READ MORE

  3. 3. Spectroscopic studies of dynorphin neuropeptides and the amyloid beta-peptide The consequences of biomembrane interactions

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Loïc Hugonin; Stockholms universitet.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TECHNOLOGY Engineering physics Biophysics; TEKNIKVETENSKAP Teknisk fysik Biofysik; Biophysics; biofysik;

    Abstract : Dynorphin A, dynorphin B and big dynorphin are endogenous opioid neuropeptides. They play an important role in a wide variety of physiological functions such as regulation of pain processing and memory acquisition. Such actions are generally mediated through the κ-receptors. READ MORE

  4. 4. Experimental studies of proton translocation reactions in biological systems Electrogenic events in heme-copper oxidases

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Håkan Lepp; Stockholms universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidase; cytochrome c oxidase; nitric oxide reductase; cbb3-type oxidase; proton pumping; uncoupling; charge-transfer; electrogenic event; flow-flash; TECHNOLOGY Engineering physics Biophysics; TEKNIKVETENSKAP Teknisk fysik Biofysik; biofysik; Biophysics;

    Abstract : Terminal heme-copper oxidases (HCuOs) are transmembrane proteins that catalyze the final step in the respiratory chain - the reduction of O2 to H2O, coupled to energy conservation by generation of an electrochemical proton gradient. The most extensively investigated of the HCuOs are the aa3-type oxidases, to which cytochrome c oxidase (CytcO) belongs, which uses energy released in the O2-reduction for proton pumping. READ MORE

  5. 5. Biophysical studies of membrane interacting peptides derived from viral and Prion proteins

    University dissertation from Stockholm : Institutionen för biokemi och biofysik

    Author : Kamila Oglęcka; Stockholms universitet.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Prion peptides; Doppel peptide; Influenza fusion peptides; peptide-membrane interactions; translocation; linear dichroism; circular dichroism; TECHNOLOGY Engineering physics Biophysics; TEKNIKVETENSKAP Teknisk fysik Biofysik; Biophysics; biofysik;

    Abstract : This thesis focuses on peptides derived from the Prion, Doppel and Influenza haemagglutinin proteins in the context of bilayer interactions with model membranes and live cells. The studies involve spectroscopic techniques like fluorescence, fluorescence correlation spectroscopy (FCS), circular and linear dichroism (CD and LD), confocal fluorescence microscopy and NMR. READ MORE