Search for dissertations about: "biomolecular interaction"

Showing result 1 - 5 of 55 swedish dissertations containing the words biomolecular interaction.

  2. 1. The protein-carbohydrate interaction : analysis of transient biomolecular complexes

    Author : Reine Johansson; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biokemi; Biochemistry;

    Abstract : .... READ MORE

  4. 2. Development and application of ultra-sensitive fluorescence spectroscopy and microscopy for biomolecular interaction studies

    Author : Lei Xu; Jerker Widengren; Gerhard Schütz; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; single molecule spectroscopy; fluorescence correlation spectroscopy; stimulated emission microscopy; cancer; biomolecular interaction; co-localization; Biological Physics; Biologisk fysik;

    Abstract : This thesis describes the development of sensitive and high-resolution fluorescence spectroscopic and microscopic techniques and their application to probe biomolecules and their interactions in solution, lipid membrane model systems and in cells. Paper I-IV are largely focused on methodological developments. READ MORE

  5. 3. Characterization of Biomolecular Interactions Using a Multivariate Approach

    Author : Karl Andersson; Mats Gustafsson; Jörgen Carlsson; Olav Kvalheim; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Chemometrics; QSAR; Interaction; kinetics; Biokemi; Biochemistry; Biokemi;

    Abstract : This thesis presents a novel bioinformatic methodology denoted the bio-chemometric approach. The methodology is designed for generation of detailed descriptions and predictions of biomolecular interactions. It is based on multivariate analysis of the sensitivity of a biomolecular interaction to multiple minor changes in the experimental conditions. READ MORE

  6. 4. QCM-D – with focus on biosensing in biomolecular and cellular systems

    Author : Erik Nilebäck; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; QCM-D; biomolecular interactions; cell-surface interaction; glycosaminoglycans; viscoelasticity; cell morphology; Quartz crystal microbalance with dissipation monitoring; surface chemistry; protein conformation;

    Abstract : The high degree of complexity in biological systems is being investigated in greater and greater detail by increasingly sophisticated sensing approaches. The quartz crystal microbalance with dissipation monitoring (QCM-D) technique stands out in this context, by probing the viscoelastic properties at interfaces. READ MORE

  7. 5. Development of Electroacoustic Sensors for Biomolecular Interaction Analysis

    Author : Henrik Anderson; Ilia Katardjiev; Björn Ingemarsson; Inger Vikholm-Lundin; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; biosensor; protein interactions; kinetics; affinity; QCM; quartz crystal microbalance; piezoelectric resonators; dissipation; motional resistance; Bioanalytical engineering; Bioanalytisk teknik; Analytical chemistry; Analytisk kemi; Teknisk fysik med inriktning mot mikrosystemteknik; Engineering Science with specialization in Microsystems Technology;

    Abstract : Biomolecular interaction analysis to determine the kinetics and affinity between interacting partners is important for the fundamental understanding of biology, as well as for the development of new pharmaceutical substances. A quartz crystal microbalance instrument suitable for kinetics and affinity analyses of interaction events was developed. READ MORE