Search for dissertations about: "bioreduction"

Showing result 1 - 5 of 6 swedish dissertations containing the word bioreduction.

  2. 1. Engineered Yeast as Biocatalyst for Stereoselective reductions of Dicarbonyl Compounds

    Author : Ted Johanson; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; chiral; screening; process optimisation; metabolic engineering; dicarbonyl; biocatalysis; yeast; bioreduction; Biotechnology; Bioteknik;

    Abstract : Chiral building blocks are needed in the chemical and pharmaceutical industries for the production of fine chemicals and pharmaceuticals. The utilisation of microorganisms and enzymes to perform stereoselective reductions of carbonyl compounds is an efficient and widely applied method for the generation of chiral molecules. READ MORE

  4. 2. Synthesis of amino- and hydroxyl-substituted bridged bicyclic compounds and their application in asymmetric catalysis

    Author : Cecilia Olsson; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; organocatalysis; asymmetric catalysis; bicyclo[2.2.1]heptane; bicyclo[2.2.2]octane; dibenzobicyclo[3.3.1]nonane; bioreduction; enzymatic kinetic resolution;

    Abstract : In this work, hydroxyl- and amino-substituted bridged bicyclic compounds based on bicyclo[2.2.1]heptane, bicyclo[2.2. READ MORE

  5. 3. Enzymatic Reduction of Ketones

    Author : Magnus Carlquist; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; inhibition; flavonoids; anthracyclines; human carbonyl reductase 1; kinetic resolution; Asymmetric bioreduction; bicyclic diketones; Saccharomyces cerevisiae; Escherichia coli; AKR; SDR;

    Abstract : Methods have been studied for the production of chiral alcohols, which are of importance in organic synthesis of pharmaceuticals, agro-chemicals and fragrances, etc., through the enzymatic or microbial reduction of ketones. READ MORE

  6. 4. Bioreduction of Carbonyl Compounds to Chiral Alcohols by Whole Yeast Cells: Process Optimisation, Strain Design and Non-Conventional Yeast Screening

    Author : Michael Katz; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bicyclic diketone; carbonyl; yeast; candida; cerevisiae; reductase; ketone; reduction; whole cell; YMR226c; YDR368w; Microbiology; bacteriology; virology; mycology; Biokemisk teknik; Biochemical technology; mykologi; virologi; Mikrobiologi; bakteriologi;

    Abstract : Chiral building blocks are needed for the production of drugs and fine chemicals, which requires the use of several synthetic routes to produce a specific enantiomer of interest. One promising approach to introduce chirality into molecules is the stereo-selective whole cell bioreduction of carbonyl compounds or ketones to the corresponding chiral alcohols. READ MORE

  7. 5. Bioreduction of carbonyl compounds to chiral alcohols by whole yeasts cells: process optimisation, strain design and non-conventional yeast screening

    Author : Michael Katz; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Chiral building blocks are needed for the production of drugs and fine chemicals, which requires the use of several synthetic routes to produce a specific enantiomer of interest. One promising approach to introduce chirality into molecules is the stereo-selective whole cell bioreduction of carbonyl compounds or ketones to the corresponding chiral alcohols. READ MORE