Search for dissertations about: "blast protein"

Showing result 1 - 5 of 27 swedish dissertations containing the words blast protein.

  2. 1. Impulse noise and brain injury. An experimental study in rats

    Author : Annette Säljö Moberg; Göteborgs universitet; []
    Keywords : apoptosis; astrocytes; brain injury; blast; c-Fos; c-Jun; c-Myc; impulse noise; ; neurons; neurofilament; NSE; rat and S-100;

    Abstract : Abstract. Pressure waves, experienced as impulse noise, affect many body organs, although most attention has been paid to the inner ear. Impulse noise is produced by e.g. READ MORE

  4. 2. Clinical and Immunological Studies in Chronic Myeloid Leukaemia

    Author : Stina Söderlund; Ulla Olsson-Strömberg; Angelica Loskog; Satu Mustjoki; Dragana Milojkovic; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic myeloid leukaemia; accelerated phase; blast crisis; tyrosine kinase inhibitor; immunology; myeloid-derived suppressor cells; cytokines; proteomics; TKI discontinuation; population-based;

    Abstract : Chronic myeloid leukaemia (CML) is characterised by the constitutively active tyrosine kinase BCR-ABL. Standard treatment with tyrosine kinase inhibitors (TKI) in the chronic phase (CP) of CML conveys excellent long-term prognosis but is associated with side effects and costs. READ MORE

  5. 3. Characterization of Genetic Abnormalities at Disease Progression of Chronic Myeloid Leukemia

    Author : Aikaterini Barbouti; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fluorescent in situ hybridization; low-copy repeats; isochromosome 17q; MSI2 HOXA9; ETV6 ABL1; BCR ABL1; chronic myeloid leukemia; blast crisis; molecular genetics; Clinical genetics; Klinisk genetik;

    Abstract : Chronic myeloid leukemia (CML) is a myeloproliferative disorder associated with the translocation t(9;22)(q34;q11) and progresses from a relatively indolent chronic phase (CP) to an accelerated phase (AP) and finally to the more aggressive blast crisis (BC). The general aim of this thesis was to identify and characterize genetic abnormalities occurring at disease progression of CML using molecular cytogenetic, molecular genetic, and bioinformatic analyses. READ MORE

  6. 4. On the antiporter-like subunits of respiratory chain Complex I - implications for the evolution and coupling mechanism of the NADH:quinone oxidoreductase enzyme complex

    Author : Cecilie Mathiesen; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; mrp; electron transport; respiration; membrane protein;

    Abstract : Complex I or NADH:quinone oxidoreductase is the largest enzyme complex, but the least understood energy coupling site in the respiratory chain of mitochondria and bacteria. No high-resolution structural information exists for this enzyme and the molecular mechanism that couples electron transfer and proton pumping is not understood. READ MORE

  7. 5. Computational identification of RNA and protein components from the Signal Recognition Particle

    Author : Magnus Alm Rosenblad; Göteborgs universitet; []
    Keywords : signal recognition particle; SRP; RNA secondary structure; non-coding RNA;

    Abstract : Problem. The signal recognition particle (SRP) is a ribonucleoprotein particle that targets proteins to the endoplasmic reticulum in eukaryotes, to the plasma membrane in Archaea and Bacteria and to the thylakoid membrane in chloroplasts of photosynthetic organisms. It has one RNA component and 1 6 proteins. READ MORE