Search for dissertations about: "bloodstream infection"

Showing result 1 - 5 of 32 swedish dissertations containing the words bloodstream infection.

2. 1. Quantitative detection of bacterial DNA in whole blood in bloodstream infection

   Author : Ingrid Ziegler; Kristoffer Strålin; Paula Mölling; Magnus Rasmussen; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bloodstream infection; bacteremia; sepsis; DNA load; quantitative PCR; droplet digital PCR; 16S rDNA;

   Abstract : This thesis aims to increase the knowledge on how quantitative PCR can be used in the diagnostics of bloodstream infections, with an emphasis on quantitative elements.In Papers I and II, we evaluated quantitative data from two commercial PCR tests for pathogen detection directly in blood, Magicplex Sepsis (I) and SeptiFast (II), from patients with suspected sepsis. READ MORE

4. 2. Clinical Impact of Bloodstream Infections – Characterization, Risk factors and Outcome

   Author : Martin Holmbom; Håkan Hanberger; Christian G. Giske; Lennart E Nilsson; Mats Fredrikson; Åse Östholm Balkhed; Ralph Peeker; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bloodstream infection BSI ; Antimicrobial resistance AMR ; Extended spectrum β-lactamase ESBL ; ESBL-producing Enterobacterales; Multidrug-resistant; Urinary tract infection; Sepsis; Epidemiology; Prehospital delay; Community-acquired BSI; Hospital-acquired BSI; Community-onset BSI;

   Abstract : Bloodstream infection (blood poisoning) and antibiotic resistance are increasing worldwide, and already cause the loss of millions of human lives each year. According to the World Health Organisation (WHO), bloodstream infections (BSIs) represent 20% of global mortality on a par with cardiac infarct, stroke, and major trauma. READ MORE

5. 3. Improved diagnosis and management of sepsis and bloodstream infection

   Author : John Karlsson Valik; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Sepsis is a severe organ dysfunction triggered by infections, and a leading cause of hospitalization and death. Concurrent bloodstream infection (BSI) is common and around one third of sepsis patients have positive blood cultures. READ MORE

6. 4. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis

   Author : Sara Cajander; Jan Källman; Kristoffer Strålin; Bo Söderquist; Per Åkesson; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; monocyte HLA-DR; sepsis; immunosuppression; bloodstream infection; HLA-DRA; CIITA; qRT-PCR;

   Abstract : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. READ MORE

7. 5. SLPI and soluble BTLA as immunological markers in severe bacterial infections

   Author : Anna Lange; Olof Hultgren; Jonas Sundén-Cullberg; Peter Bergman; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SLPI; sBTLA; sepsis; bloodstream infection; pneumonia;

   Abstract : Clinical presentation, and outcome of infections are affected by host-, and etiology- (focus of infection and pathogen) related factors. The immune response is controlled by a network of regulating pathways. READ MORE