Search for dissertations about: "brain aging"

Showing result 1 - 5 of 115 swedish dissertations containing the words brain aging.

  2. 1. The aged brain : structural changes and cognitive function

    Author : Hedvig Söderlund; Lena Lyons; Stockholms universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Brain; Cognitive processes; Aging; Åldrandets psykologi; Kognitiva processer; Hjärna;

    Abstract : .... READ MORE

  4. 2. Telomeres and the brain : an investigation into the relationships of leukocyte telomere length with functional and structural attributes of the brain

    Author : Mikael Wikgren; Karl-Fredrik Norrback; Rolf Adolfsson; Göran Roos; Thomas Karlsson; Brenda Penninx; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APOE; aging; atrophy; brain; cognition; cortisol; depression; hippocampus; HPA axis; MRI; stress; telomere length; white matter hyper-intensities.;

    Abstract : Telomeres are the outermost parts of linear chromosomes. They consist of tandemly repeated non-coding short nucleotide sequences (TTAGGG in all vertebrates), in humans spanning over the last 2 to 15 kilobase pairs of the chromosome. Due to the end-replication problem, telomeres shorten with each cellular division. READ MORE

  5. 3. The architecture of the aging brain : functional reorganization, structural changes, and the role of dopamine receptors

    Author : Robin Pedersen; Alireza Salami; Anna Rieckmann; Anders Wåhlin; Lars Nyberg; Roser Sala-Llonch; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain architecture; functional connectivity; dopamine; aging; cognition; memory; functional magnetic resonance imaging; positron emission tomography; graph theory; Laplacian eigenmapping; gradient;

    Abstract : Aging is associated with reorganization of functional brain architecture, potentially leading tocognitive decline in older age. However, the mechanisms responsible for alterations in functionalbrain architecture remain poorly understood. READ MORE

  6. 4. The aging brain and changes in cognitive performance : Findings from morphometry and quantitative susceptibility mapping of iron

    Author : Ninni Persson; Håkan Fischser; Kristine B. Walhovd; Stockholms universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; brain aging; volumes; ndividual differences; QSM; cognitive aging; iron; episodic memory; fluid-; crystalized abilities; sex differences; gender differences; Psychology; psykologi;

    Abstract : Brain aging is a heterogeneous phenomenon, and this thesis illustrates how the course of aging can vary within individuals over time and between individuals as a function of age, sex, and genetic variability. We used two contrasts from magnetic resonance imaging (MRI), namely spin-lattice T1-weighted imaging, and quantitative susceptibility mapping (QSM) from gradient-echo images, to picture the aging brain, by means of morphometric measures and brain-iron concentrations. READ MORE

  7. 5. Cerebral arterial pulsatility imaging using 4D flow MRI : methodological development and applications in brain aging

    Author : Tomas Vikner; Anders Wåhlin; Anders Eklund; Jan Malm; Lars Nyberg; Susanne Schnell; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; 4D flow MRI; medical image analysis; cerebral hemodynamics; arterial pulsatility; DCE MRI; blood-brain barrier; white matter lesions; perivascular spaces; cerebral small vessel disease; hippocampus; cognition; aging; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Abstract : 4D flow magnetic resonance imaging (MRI) is increasingly recognizedas a versatile tool to assess arterial and venous hemodynamics. Cerebral arterial pulsatility is typically assessed by analyzing flow waveforms over the cardiac cycle, where flow amplitude is a function of cardiac output, central arterial stiffness, and cerebrovascular resistance and compliance. READ MORE