Search for dissertations about: "brain cancer in children"

Showing result 1 - 5 of 36 swedish dissertations containing the words brain cancer in children.

  2. 1. Tumors associated with Hereditary Nonpolyposis Colorectal Cancer: Defective Mismatch Repair and Familial Risk of Cancer

    Author : Kajsa Ericson Lindquist; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; cancerology; Cytologi; onkologi; cancer; Multiple Tumors; Hereditary Nonpolyposis Colorectal Cancer; Cytology; Cohort study; Population based; Familial Risk of Cancer; Immunohistochemistry; MSH2; MSH6; MLH1; Microsatellite Instability; Soft Tissue Sarcomas; Cancer of the Upper Urinary Tract; Cancer of the Small Intestine; Colorectal Cancer;

    Abstract : Inactivation of the DNA mismatch repair (MMR) system is a tumorigenic mechanism involved in 15-20% of tumor types such as colorectal and endometrial cancer and is specifically associated with the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome. These MMR defective tumors are characterized by microsatellite instability (MSI), a phenomenon that reflects alterations in length of repeated sequences, and 90% of MSI tumors show loss of immunohistochemical expression for the MMR protein affected. READ MORE

  4. 2. Balancing - Cancer from a primary care perspective. Diagnosis, posttraumatic stress, and end-of-life care

    Author : Hans Thulesius; Allmänmedicin och samhällsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medicinsk utbildning; Cytology; grounded theory; brain tumor; leukemia; child; ovarian cancer; breast cancer; prognosis; end-of-life care; screening; posttraumatic stress; diagnosis; primary care; Cancer; family practice; oncology; cancerology; Cytologi; onkologi; cancer; General practice; medical training; Allmän medicinsk utövning;

    Abstract : This thesis explores cancer from a primary care perspective covering three areas: diagnosis, posttraumatic stress disorder (PTSD), and end-of-life care. We analyzed patient records of every child diagnosed with a malignancy in a defined area. During 12 years 68 children were diagnosed (incidence 14/100,000). READ MORE

  5. 3. Epidemiological aspects on malignant diseases in childhood

    Author : Ann Charlotte Dreifaldt; Lennart Hardell; Ulf Flodin; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; childhood cancer; incidence rates; persistent organic pollutants; breast-feeding; MEDICINE; MEDICIN; Oncology; Onkologi; Medicin; Medicine; Onkologi; Oncology;

    Abstract : The trends of malignant diseases in children aged 0 to 14 years, reported to the Swedish Cancer Registry 1960–1998 (n=9 298) were analyzed. The most common diagnoses were leukemia, 29.7%, tumors of the central nervous system (CNS), 27.6%, and lymphomas, 10. READ MORE

  6. 4. Experimental models of pediatric brain tumors. Establishment, immunophenotyping and clinical implications

    Author : Emma Sandén; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric Brain Tumor; Experimental model; Immunotherapy; Immune monitoring; Medulloblastoma;

    Abstract : Brain tumors are the most common solid tumors in children. Current treatment protocols fail in 25% of patients and are associated with significant long-term adverse effects in survivors. READ MORE

  7. 5. Neuroblastoma Cell Differentiation: The Role of Neurotrophin Receptor Signaling and N-myc Expression

    Author : Anders Edsjö; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytologi; onkologi; cancer; oncology; cancerology; Cytology; N-myc.; trkC; trkB; trkA; neurotrophins; Neuroblastoma; sympathetic nervous system;

    Abstract : Neuroblastoma is a tumor of sympathetic nervous system derivation, mostly afflicting young children. This thesis is focused on a group of receptor proteins for neurotrophic factors, the Trk family, and on N-Myc, a transcription factor, all important in the formation of the sympathetic nervous system as well as in determining neuroblastoma patient outcome. READ MORE