Search for dissertations about: "brain tumor thesis RADIOLOGY"

Showing result 1 - 5 of 11 swedish dissertations containing the words brain tumor thesis RADIOLOGY.

  1. 1. Proton Magnetic Resonance Spectroscopy in Brain Tumors - Clinical Applications

    Author : Isabella Björkman-Burtscher; Lund Diagnostisk radiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiology; Clinical physics; Localization; Abscess; Brain; Tumor; Spectroscopy; Magnetic Resonance; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Abstract : Aims: · to present a test phantom and test method for evaluation of proton magnetic resonance spectroscopy (1H-MRS) single volume localization techniques regarding signal contamination; · to describe the introduction of 1H-MRS in the daily routine of a standard MR-unit; · to evaluate the possibilities offered by 1H-MRS to improve preoperative diagnostic accuracy in patients scheduled for stereotactic biopsy of intracranial mass lesions; · to evaluate the possibilities offered by 1H-MRS to improve diagnostics and therapy control in patients with brain abscesses; · to test the hypothesis that 1H-MRS might be useful for differentiation of brain tumors, based on metabolic changes in tissue across brain lesions or surrounding tissue. Results and conclusions: · The test phantom and test method allow quality assessment with good reproducibility. READ MORE

  2. 2. Nuclear magnetic resonance and microcirculation: The influence of pulsatile brain-tissue motion on measurements of intravoxel incoherent motion and assessment of haemodynamics using exo- and endogenous tracers

    Author : Ronnie Wirestam; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diagnostic radiology; cortical activation; diffusion; tumor; tumour; ischemic stroke; ischaemic stroke; tracer kinetics; bolus tracking; phase mapping; brain motion; intracranial dynamics; blood flow; haemodynamics; vascularity; MRS; perfusion; MRI; magnetic resonance; Clinical physics; radiology; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Abstract : In this project, the potential of magnetic resonance (MR) imaging and spectroscopy in studies of microcirculation and haemodynamics was evaluated. The spatial and temporal characteristics of human pulsatile brain-tissue movements in healthy individuals, relevant for the understanding of the cerebrospinal-fluid (CSF) circulation and the pathogenesis of hydrocephalus, were thoroughly investigated. READ MORE

  3. 3. Probing brain microstructure with multidimensional diffusion MRI: Encoding, interpretation, and the role of exchange

    Author : Björn Lampinen; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MRI; Diffusion; Human; Brain; Microstructure; Fysicumarkivet A:2021:Lampinen;

    Abstract : Diffusion MRI (dMRI) is a non-invasive probe of human brain microstructure. It is a long-standing promise to use dMRI for ‘in vivo histology’ and estimate tissue quantities. However, this faces several challenges. First, the microstructure models used for dMRI data are based on assumptions that may cause erroneous interpretations. READ MORE

  4. 4. Guidance and Visualization for Brain Tumor Surgery

    Author : Filipe Miguel Maria Marreiros; Örjan Smedby; Sandro Rossitti; Karin Wårdel; Anders Ynnerman; Ole Jacob Elle; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Image guidance and visualization play an important role in modern surgery to help surgeons perform their surgical procedures. Here, the focus is on neurosurgery applications, in particular brain tumor surgery where a craniotomy (opening of the skull) is performed to access directly the brain region to be treated. READ MORE

  5. 5. MRI at 3 T of brain functions and fibre tracts adjacent to intracranial tumors

    Author : Danielle van Westen; Lund Diagnostisk radiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering; radiology; tomography; Clinical physics; Medicin människa och djur ; Medicine human and vertebrates ; somatosensory cortex; diffusion magnetic resonance imaging; neoplasms; Functional Magnetic Resonance Imaging;

    Abstract : The aims of the studies were: to evaluate the spatial resolution of fMRI at 3 T by studying fingersomatotopy in area 3 b of the primary sensory area (Paper 1); to investigate the potential of fMRI at 3T as a clinical tool for preoperative evaluation of patients with intracranial tumors (Paper 2); to investigate the effect of glioma resection on the spatial extent of fMRI activation as compared to the normal within-subject variability (Paper 3); to determine whether the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) can distinguish tumor-infiltrated edema of gliomas from pure edema of meningiomas and metastases (Paper 4). Results: Strict somatotopic organisation in the primary sensory cortex was shown in the group average; at the subject level the thumb was located laterally, anteriorly and inferiorly to the little finger in 94 % of subjects (Paper 1). READ MORE