Search for dissertations about: "bronchial epithelial cells"

Showing result 1 - 5 of 47 swedish dissertations containing the words bronchial epithelial cells.

  1. 1. New aspects of allergic mechanisms and innate immunity in asthma. Alarmins as upstream mediators of asthma inflammation

    Author : Sangeetha Ramu; Lunds universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; Aeroallergens; Airway inflammation; Bronchial epithelial cells; Bronchial smooth muscle cells; Metabolic DAMPs; Proteases; Allergen immunotherapy; Mast cells; Viral infections; innate immunity;

    Abstract : Asthma is a chronic inflammatory lung disease affecting over 300 million individuals worldwide. Both respiratory viral infections and aeroallergens have been identified as important risk factors for asthma. READ MORE

  2. 2. Immunopathological and Structural Alterations in Difficult to Control Asthma

    Author : Anders Bergqvist; Luftvägsinflammation; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe asthma; bronchial thermoplasty; airway smooth muscle; neuroendocrine cells; inflammation; immune cells; remodelling;

    Abstract : Asthma is a chronic respiratory disorder affecting an estimated 300 million people worldwide. Most patients with asthma can be controlled with bronchodilators and low to moderate dose inhaled corticosteroids. However, an estimated 5-10% of the population presents a more troublesome disease, often referred to as severe asthma. READ MORE

  3. 3. Effects of Th-1 and Th-2 Cytokines and Reactive Oxygen Species on Normal Human Bronchial Epithelial Cells

    Author : Caroline Kampf; Benjamin Gaston; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; ytokines; desmosomes; focal adhesions; free radicals; hypochlorous acid; nitric oxide; normal human bronchial epithelial cells; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Epithelial damage and shedding of the epithelium are common observations in many airway diseases such as asthma, Sjögren’s syndrome, chronic obstructive pulmonary disease and cystic fibrosis. The ability of the cells to attach to each other and/or to the matrix seems to be altered. READ MORE

  4. 4. Cell Contacts and Airway Epithelial Damage in Asthma

    Author : Shahida Shahana; Godfried Roomans; Rolf Odselius; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anatomy; Desmosomes; tight junctions; major basic protein; eosinophil; cytokines; epithelial damage.; Anatomi; Anatomy; Anatomi;

    Abstract : Airway epithelial damage is commonly found in asthma patients. Epithelial damage was investigated with special reference to contacts between epithelial cells.Eosinophils, common in allergic asthma, secrete cationic proteins, particularly major basic protein (MBP). READ MORE

  5. 5. Activation of lung epithelial cells by group 2 mite allergens

    Author : Camilla Österlund; Anders Bucht; Thomas Sandström; Jan Wahlström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; group 2 mite allergens; Der p 2; Der f 2; Eur m 2; Lep d 2; airway epithelium; lungmedicin; Lung Medicine;

    Abstract : Throughout many parts of the world house dust mites (HDM) are considered as a major source of indoor aeroallergens and they are powerful inducers of allergic diseases. Proteolytic HDM allergens are recognised as being able to directly activate respiratory epithelial cells and thereby actively participate in innate immune responses. READ MORE