Search for dissertations about: "cDNA differential display"
Showing result 1 - 5 of 8 swedish dissertations containing the words cDNA differential display.
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1. Identification of abnormally expressed genes in skeletal muscle contributing to insulin resistance and type 2 diabetes
Abstract : The metabolic defects of insulin resistance and type 2 diabetes can result from changes in gene expression and protein functions due to genetic and environmental influences. The aim of this study was to identify abnormally expressed genes associated with insulin resistance or type 2 diabetes, and further to test whether possible defects are inherited or acquired. READ MORE
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2. Molecular mechanisms involved in glioma cell interactions in vitro and studies of PDGF B transcript variants
Abstract : Glioblastoma multiforme is a malignant brain tumor characterized by heterogeneity.Interactions between heterogeneous tumor cells are supposed to affect the behavior of awhole tumor cell population. READ MORE
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3. Redesign of substrate specificity of glutathione transferase and glutathione reductase : Enzyme engineering by directed mutagenesis, phage-display selection and DNA shuffling
Abstract : Human glutathione transferase (GST) A1-1 was expressed in fusion with the phage gene IIIproduct and a library of phage-displayed GST mutants was constructed by randomization of fouractive-site residues. Variant GSTs were isolated by mechanism-based phage display selection, using an immobilized transition-state analog of a nucleophilic aromatic substitution (SNAr) reaction. READ MORE
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4. Innate immune gene expression and function studied in insects and mammals
Abstract : Insects and mammals possess innate immune responses to effectively recognize and eliminate invading microorganisms. Insects, who share with mammals conserved molecules for immune defense, are good model systems for innate immunity studies. READ MORE
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5. Biotic and abiotic stress in microorganisms and plants: Some Mechanisms of Stress and Programmed Cell Death. Genetic Engineering Approaches Towards Improved Stress Tolerance
Abstract : Various forms of stress, such as biotic and abiotic stress, were studied in microorganisms and plants to learn more about the underlying mechanisms of such stress and potential genetic engineering strategies towards stress tolerance. An antifreeze protein from winter flounder, expressed in E. READ MORE