Search for dissertations about: "cadherins"

Showing result 1 - 5 of 8 swedish dissertations containing the word cadherins.

  1. 1. The significance of blood vessels in organogenesis and cadherins in exploratory behaviour

    Author : Josefina Edsbagge; Göteborgs universitet; []
    Keywords : pancreas; sphingosine-1-phosphate; endothelium; epithelial-to-mesenchymal interactions; ; Cre loxP-system; cadherins; rearing;

    Abstract : Organogenesis of epithelial organs requires interaction between epithelial andmesenchymal tissues. In pancreas development three different mesenchymal derivedstructures, the notochord, the endothelial cells and the splanchnic mesenchyme inducespecification, growth and further differentiation of the pancreatic epithelium. READ MORE

  2. 2. Molecular regulation of thyroid development. New mechanisms of normal and defective morphogenesis

    Author : Henrik Fagman; Göteborgs universitet; []
    Keywords : thyroid; congenital hypothyroidism; thyroid dysgenesis; cadherins; pharyngeal arch arteries; Shh; Tbx1;

    Abstract : Congenital hypothyroidism (CH) is untreated a major cause of mental retardation. The majority of cases are due to malformations of the gland (dysgenesis). Little is known of molecular mechanisms regulating thyroid morphogenesis. READ MORE

  3. 3. Classical cadherins and the thyroid. Studies on organ development and epithelial differentiation

    Author : Mats Grände; Göteborgs universitet; []
    Keywords : Thyroid; cadherin; TGF-; EGF; MEK; development; EMT;

    Abstract : The cadherins are key regulators of tissue patterning and organ formation. E-cadherin is important for cell-cell adhesion and promotes epithelial morphogenesis and maintenance of the epithelial phenotype. READ MORE

  4. 4. The role of cell adhesion molecules in tissue formation and organogenesis

    Author : Farzad Esni; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell adhesion cadherins N-CAM pancreas development mouse organogenesis;

    Abstract : Cell adhesion molecules (CAMs) are cell surface glycoproteins that promote connection between two adjacent cells or between a cell and extra cellular matrix. These interactions are essential for tissue organisation during development and for the maintenance of tissue integrity in adult organisms. READ MORE

  5. 5. Manipulating neural stem cells

    Author : Malin Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The stem cell field is a fairly young but fast growing scientific field. Our understanding of stem cells has changed tremendously over the last couple of decades. This in mainly due to the development of new techniques that has enabled us to study stem cells from a completely new perspective. READ MORE