Search for dissertations about: "cancer cell permeability"
Showing result 1 - 5 of 26 swedish dissertations containing the words cancer cell permeability.
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1. Regulation of VEGFR2 signaling in angiogenesis and vascular permeability
Abstract : Angiogenesis and vascular permeability occur in physiological and pathological conditions. Angiogenesis denotes the process of blood vessel formation from preexisting quiescent vessels. READ MORE
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2. CD93 in regulation of vascular function and tumour progression
Abstract : To achieve successful vascular targeting in cancer, a better understanding of the molecular mechanisms that lead to tumour vascular abnormalities is required. The transmembrane protein CD93 is highly expressed in the vasculature of several tumours including glioblastoma and has emerged as a potential anti-angiogenic target. READ MORE
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3. Vascular targeting for enhanced cancer immunotherapy
Abstract : Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The scope of this thesis is to understand the role of the vasculature in anti-tumor immunity and thereby to improve cancer immunotherapy. READ MORE
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4. Role of TGFβ-induced hyaluronan-CD44 signaling in cancer progression
Abstract : Hyaluronan, a prevalent glycosaminoglycan of the extracellular space often accumulates in pathological conditions, such as chronic inflammation, infection, and cancer. Hyaluronan synthase HAS2 has been responsible for the synthesis and deposition of hyaluronan in a variety of tumors. READ MORE
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5. Investigating histidine-rich glycoprotein and T cell-specific adaptor as potential biomarkers and therapeutic targets
Abstract : The endothelial cell (EC), the most important cell type in blood vessels, lines the vessel wall and provides vessel integrity. EC function is tightly regulated, and its dysregulation is a key element in many diseases including cardiovascular disease, cancer and several diseases of the eye. READ MORE