Search for dissertations about: "cancer drugs"
Showing result 1 - 5 of 497 swedish dissertations containing the words cancer drugs.
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1. Quiescent cancer cells : Three-dimensional cell models for evaluation of new therapeutics
Abstract : Inadequate metabolic conditions in solid tumors lead to the formation of quiescent cancer cells that are suspended in a transient cell cycle arrest. When conditions change, quiescent cancer cells can re-enter the cell cycle and cause recurrence. READ MORE
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2. Cancer in organ transplant recipients
Abstract : Tens of thousands of transplantations are performed around the world each year. Organ transplant recipients (OTR) are obliged to receive life-long medical treatment with immunosuppressive drugs to ensure graft function. However, such medications entail an increased risk of developing a broad spectrum of malignancies, especially skin cancer. READ MORE
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3. The proteasome as a target for cancer therapy
Abstract : The main objective of this PhD thesis was to evaluate the significance of proteasome genes as prognostic markers for different cancer types and identify specific cancer forms that respond to proteasome inhibition. The proteasome (PSM) plays an important role in maintaining cellular proteostasis and degrades the majority of proteins that require breakdown in the cell. READ MORE
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4. Improved Nutritional Support in Cancer Patients
Abstract : Weight loss and other nutritional problems are common in cancer patients. The problems are of importance for response to treatment and survival and the well-being of the patients.Nutritional support can be carried out in different ways. READ MORE
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5. Patient-derived scaffolds as a 3D model for breast cancer
Abstract : Breast cancer is the most common cancer form in women worldwide. Many patients will have recurrent disease and more efficient targeted therapies are needed. The tumor microenvironment is a heterogenous complex mix of cells and components influencing critical cancer processes including progression, signaling and invasion. READ MORE