Search for dissertations about: "cb1 receptors"

Showing result 1 - 5 of 13 swedish dissertations containing the words cb1 receptors.

  2. 1. Development of cannabinoid subtype-1 (CB1) receptor ligands for PET

    Author : Sean R Donohue; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Introduction: Abnormalities in brain cannabinoid subtype-1 (CB1) receptor concentrations and/or signaling pathways may be involved in a variety of psychiatric and neurodegenerative disorders. There is a strong need to image and quantify brain CB1 receptor concentrations in living humans under baseline and diseased conditions. READ MORE

  4. 2. In vivo imaging of the cannabinoid CB1 receptor using positron emission tomography

    Author : Garth Terry; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The actions of marijuana (cannabis) are mediated by receptors (primarily the cannabinoid CB1 receptor) that have unusually high density and wide distribution in brain. In addition to mediating the effects of exogenous drugs like cannabis, these receptors also receive signals from endogenous cannabinoids (endocannabinoids), which modulate the release of several other neurotransmitters. READ MORE

  5. 3. New molecular markers in mantle cell lymphoma : studies of cannabinoid receptors, 5-lipoxygenase and SOX11

    Author : Xiao Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that accounts for 5-10% of all lymphomas and tends to occur in older adults with a higher incidence in males. The genetic hallmark of this neoplasm is the t(11;14) translocation which results in overexpression of nuclear cyclin D1. READ MORE

  6. 4. The endocannabinoid system : a translational study from Achilles tendinosis to cyclooxygenase

    Author : Emmelie Björklund; Christopher Fowler; Peter Zygmunt; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The endogenous cannabinoids anandamide (arachidonoyl ethanolamide, AEA) and 2-arachidonoyl glycerol (2-AG) exert their effect by activating cannabinoid receptors (CB). These receptors mediate a broad range of physiological functions such as beneficial effects in pain and inflammation, although little is known about the expression of CB receptors in human pain conditions. READ MORE

  7. 5. Studies of cannabinoid receptor 1 in mantle cell lymphoma

    Author : Kristin Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that affects older individuals and has a male predominance. MCL has one of the worst prognoses among lymphomas and currently there is a search for a curative therapy. READ MORE