Search for dissertations about: "cell detection"

Showing result 16 - 20 of 768 swedish dissertations containing the words cell detection.

  2. 16. Mechanisms regulating Natural Killer Cell Cytotoxicity

    Author : Hanna van Ooijen; Björn Önfelt; Karl-Johan Malmberg; Karolin Guldevall; Morgan Huse; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Natural Killer cell; Live-cell microscopy; Single cell; 3D; Microwell;

    Abstract : Over the last 50 years, cancer survival rates have steadily improved thanks to earlier detection and novel treatment regimens. For example, drugs that act on the immune system, so-called immunotherapy, have drastically increased the prospect of survival for patients suffering from some of the most aggressive cancer types including advanced malignant melanoma. READ MORE

  4. 17. p63 – from expression to function : studies of normal oral mucosa and squamous cell carcinoma of the head and neck

    Author : Niklas Thurfjell; Karin Nylander; Phillip Coates; Göran Roos; Luisa Guerrini; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; p63; SCCHN; p53; BRCA1; Pathology; Patologi;

    Abstract : The human p63 gene discovered in 1997 encodes a series of protein isoforms that differ in their N- and/or C-terminal sequences. These isoforms have widely differing properties in promoting or repressing p53-related functions such as growth arrest and apoptosis. READ MORE

  5. 18. Microfluidic Compartmentalization for Smart Materials, Medical Diagnostics and Cell Therapy

    Author : Emre Iseri; Wouter van der Wijngaart; Nicole Pamme; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microfluidics; microfabrication; compartmentalization; partitioning; droplet microfluidics; self-assembly; 3D microarrays; soft composites; beads; particles; core-shell particle; point-of-care; diagnostics; dipstick; digital bioassays; lab-on-a-chip; urinary tract infection; bacteria detection; E. coli; cell encapsulation; hydrogel; cell therapy; spider silk; magnetic metamaterials.; Mikrofluidik; mikrotillverkning; kompartmentalisering; partitionering; droppmikrofluidik; självmontering; 3D-mikromatriser; mjuka kompositer; pärlor; partiklar; kärna-skalpartikel; vårdpunkt; diagnostik; mätsticka; digitala bioanalyser; laboration-a-chip; urinvägsinfektion; bakteriedetektering; E. coli; cellinkapsling; hydrogel; cellterapi; spindelsilke; magnetiska metamaterial.;

    Abstract : The organisation of fluids in small compartments is ubiquitous in nature, such as in the cellular composition of all life. This work explores several engineering avenues where microscale fluid compartmentalization can bring novel material properties or novel functionality in life sciences or medicine. READ MORE

  6. 19. Integration of Molecular Biology and Morphology in Effusions with Focus on in situ Detection of Telomerase and its Components

    Author : Nooreldin Zendehrokh; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pathological anatomy; Patologi allmän ; patologisk anatomi; Diagnostics; Diagnostik; cancer; TRAP in situ; onkologi; Cytologi; cancerology; oncology; Cytology; Medicin människa och djur ; Medicine human and vertebrates ; General pathology; Telomerase;

    Abstract : Clinical cytology is a rapid method to detect malignancy in effusions of the serous cavities, but the morphological characteristics of the cells do not always allow diagnosis and a specific marker for malignant cells would improve the diagnostic performance. Telomerase adds telomere repeats to the chromosome ends. READ MORE

  7. 20. Application of Padlock Probe Based Nucleic Acid Analysis In Situ

    Author : Sara Henriksson; Mats Nilsson; Ulf Landegren; Harvest Gu; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probe; rolling circle amplification; single cell gel electrophoresis assay; comet assay; Crimean Congo hemorrhagic fever virus; Molecular medicine; Molekylär medicin; Molekylär medicin; Molecular Medicine;

    Abstract : The great variation displayed by nucleic acid molecules in human cells, and the continuous discovery of their impact on life, consequently require continuous refinements of molecular analysis techniques. Padlock probes and rolling circle amplification offer single nucleotide discrimination in situ, a high signal-to-noise ratio and localized detection within cells and tissues. READ MORE