Search for dissertations about: "cell replacement therapies"
Showing result 1 - 5 of 48 swedish dissertations containing the words cell replacement therapies.
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1. Cell Replacement Therapy for Parkinson's Disease - Evaluating the potential of autologous grafting
Abstract : .... READ MORE
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2. Responses of fibroblasts and chondrosarcoma cells to mechanical and chemical stimuli
Abstract : Osteoarthritis is an inflammation-related disease that progressively destroys joint cartilage. This disease causes pain and stiffness of the joints, and at advanced stages, limitations to the movement or bending of injured joints. Therefore, it often restricts daily activities and the ability to work. READ MORE
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3. A long and winding road: Differentiating human embryonic stem cells into dopaminergic neurons
Abstract : Parkinson’s disease is a progressive neurodegenerative disorder. Since the motor manifestations of the disease is associated with the loss of dopaminergic (DAergic) neurons in the substantia nigra pars compacta, cell replacement therapy is a promising approach for treatment. READ MORE
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4. Transcriptional profiling of human embryonic stem cells and their functional derivatives
Abstract : Human embryonic stem cells (hESCs) represent populations of pluripotent, undifferentiated cells with unlimited replication capacity, and with the ability to differentiate into any functional cell type in the human body. Based on these properties, hESCs and their derivatives provide unique model systems for basic research on embryonic development. READ MORE
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5. Modelling Human Developmental Hematopoiesis. Towards in vitro Generation of Human Hematopoietic Stem Cells
Abstract : The possibility to manufacture hematopoietic stem cells (HSCs) in the laboratory would provide an indefinite source of cells for patients requiring bone marrow transplantation. Moreover, combined with the progress in gene editing techniques, it would provide a novel platform for gene and cell replacement therapies for a range of currently incurable congenic and acquired disorders. READ MORE