Search for dissertations about: "cell-based assay"
Showing result 1 - 5 of 40 swedish dissertations containing the words cell-based assay.
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1. Rift Valley fever : consequences of virus-host interactions
Abstract : Rift Valley fever virus (RVFV) is a mosquito-borne virus which has the ability to infect a large variety of animals including humans in Africa and Arabian Peninsula. The abortion rate among these animals are close to 100%, and young animals develop severe disease which often are lethal. READ MORE
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2. Deciphering Binding Patterns of Therapeutic Antibodies with Immune Cells : From Method Development to Application
Abstract : Reversible binding, for example between signaling molecules and receptors on the cell surface, is one of the main means to communicate information in cellular systems. Knowledge about how molecules interact is crucial for both understanding biological function and for therapeutic intervention. READ MORE
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3. Monitoring of Cellular Dynamics with Focus on Electrochemical Detection Techniques
Abstract : This thesis presents work in two main areas of focus, the development of electroanalytical techniques to monitor the dynamics of cellular processes as well as design and fabrication of microelectrode chips for electrochemical detection as well as a prototype microfluidic system to be used for cell analysis and culturing. The electrochemically monitored cellular parameters were the cellular redox environment (CRE), cell adhesion and exocytosis. READ MORE
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4. Rapid sample preparation and bioanalytical techniques for efficient screening of organic pollutants in the environment
Abstract : Large numbers of samples often need to be prepared and analysed in surveys of organic pollutants in the environment, but while the methods commonly used in such surveys can provide abundant detail they are generally costly, time-consuming and require large amounts of resources, so there is a need for simpler techniques. The work underlying this thesis assessed the potential utility of more convenient sample preparation and bioanalytical techniques for rapidly screening various environmental matrices that could be useful complements to higher resolution methods. READ MORE
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5. Strategies to improve and balance the expression levels of recombinant proteins in mammalian cell lines
Abstract : Proteins are the building blocks of all living organisms enabling us to function and survive. There are more than 100,000 different proteins in the human body performing a variety of vital tasks. READ MORE