Search for dissertations about: "cell-surface molecule"

Showing result 1 - 5 of 81 swedish dissertations containing the words cell-surface molecule.

  2. 1. Streptococcal cell surface proteins : structure and gene characterisation

    Author : Viatcheslav Katerov; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; mycology; virology; bacteriology; virologi; mykologi; Microbiology; bakteriologi;

    Abstract : Streptococcus pyogenes (group A streptococci, GAS) is a potent human pathogen known to express a number of cell surface associated virulence factors. It is an established fact that these different surface proteins play an important role during infection. READ MORE

  4. 2. Variant antigens at the infected red cell surface in Plasmodium falciparum malaria

    Author : Victor Fernandez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Plasmodium falciparum; blood stages; variant antigens; var PfEMP1; rif RIFIN; adhesive phenotypes; cytoadherence; endothelial receptor; PECAM-1 CD31; rosetting; heparan sulphate;

    Abstract : Disease severity in Plasmodium falciparum infections is, to a large extent, a consequence of the parasite's efficient escape from die human host defences. Sequestration and antigenic variation are two evasion mechanisms featured by P.falciparum. READ MORE

  5. 3. Gene Polymorphisms and Related Cell Markers in Periodontitis Lesions

    Author : Mauro Donati; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allele; B-lymphocyte; cell-surface molecule; cytokine; gene expression; genotype; gingivitis; host response; inflammation; periodontal disease;

    Abstract : Inflammatory and immune reactions to microbial plaque are the predominant features of periodontitis. Epidemiological studies revealed that differences in periodontitis among individuals could not be explained by differences in oral hygiene alone and that not everybody is equally susceptible. READ MORE

  6. 4. Interactions between herpes simplex virus type 1 glycoprotein C and cell surface glycosaminoglycans

    Author : Kristina Mårdberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Herpes simplex virus-1; glycoprotein C; virus receptor; glycosaminoglycans; heparan sulfate; chondroitin sulfate;

    Abstract : The cell surface glycosaminoglycan (GAG) heparan sulfate (HS) serves as an initial receptor for herpes simplex virus type 1 (HSV-1) and virus attachment to the HS molecule is mediated by the envelope glycoprotein C (gC). In the first part of this thesis, we aimed to define the HS-binding domain of viral gC. READ MORE

  7. 5. Interaction of herpes simplex virus with cell surface glycosaminoglycans as a target for antiviral intervention

    Author : Kicki Bergefall; Göteborgs universitet; []
    Keywords : HSV; glycoproteins; glycosaminoglycans; virus receptor; antiviral drugs;

    Abstract : Herpes simplex virus (HSV) infections in humans are predominantly manifested as oral cold sores or genital ulcers. As HSV infects cells by interaction with cell surface heparan sulfate (HS) and/or chondroitin sulfate (CS), the aim of the research work presented in this thesis was to explore the possibility of antiviral intervention with compounds that mimic HS or CS. READ MORE