Search for dissertations about: "central nervous system physiology and pharmacology"

Found 2 swedish dissertations containing the words central nervous system physiology and pharmacology.

2. 1. Vascular effects of neuropeptides and UDP-β-S and alterations after stroke

   Author : André Erdling; Neurokirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The aim of this thesis is to investigate the changes in vasoactive intestinal peptide (VIP) and calcitonin gene-related peptide(CGRP) and P2Y6-mediated signaling following experimental subarachnoid hemorrhage (SAH) and transient middle cerebral artery occlusion (tMCAO). VIP and CGRP are among the most powerful vasodilators known to man while P2Y6 mediates strong vasoconstriction in cerebral blood vessels. READ MORE

4. 2. WNT/FZD signaling : an odyssey from molecular pharmacology to brain (patho)physiology

   Author : Jacomijn P Dijksterhuis; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The 19 members of the lipoglycoprotein family of WNTs interact with the highly conserved cysteine-rich domain (CRD) of ten members of the Frizzled (FZD1-10) family. The seven transmembrane-spanning surface receptors are listed as G protein-coupled receptors and are known to interact with heterotrimeric G proteins as well as the scaffolding protein disheveled. READ MORE