Search for dissertations about: "central sensitization"

Showing result 1 - 5 of 36 swedish dissertations containing the words central sensitization.

  2. 1. Nitric Oxide Exchange in Central and Peripheral Airways : Determinants in Health and Respiratory Disease

    Author : Andrei Malinovschi; Christer Janson; Kjell Alving; Lena Holm; Elisabeth Bel; Uppsala universitet; []
    Keywords : exhaled nitric oxide; alveolar NO; bronchial NO flux; extended NO analysis; asthma; smoking; snus; IgE-sensitization; pharyngo-oral tract; nitrate; nitrite; pulmonary hypertension;

    Abstract : Background: Exhaled nitric oxide (NO) is a marker of eosinophilic steroid-sensitive inflammation in the airways of patients with respiratory disease. Moreover, information about the localization of inflammation in the respiratory tree is obtained by estimates of bronchial and alveolar contributions to exhaled NO. READ MORE

  4. 2. Irritable bowel syndrome - a disorder of gut-brain interaction

    Author : Irina Midenfjord; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Irritable Bowel Syndrome; gastrointestinal symptom severity; anxiety; depression; neurophysiological aberrations; psychological alterations; central sensitization;

    Abstract : Irritable bowel syndrome (IBS) is a common and multifactorial functional gastrointestinal (GI) disorder characterized by altered gut-brain communication. Due to the complexity of gut-brain interactions, the aim of this thesis was to enhance the understanding of associations between GI symptom severity and measures from multiple levels along the gut-brain axis in IBS patients. READ MORE

  5. 3. Experimental Aspects on Chronic Whiplash-Associated Pain

    Author : Dag Lemming; Björn Gerdle; Per Hansson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neck injury; whiplash-associated disorders; chronic pain; central sensitization; pain assessment; drug challenges; MEDICINE; MEDICIN;

    Abstract : Introduction: Chronic pain after whiplash trauma (chronic WAD) to the neck is still a common clinical problem in terms of pain management, rehabilitation and insurance claims. In contrast to the increased knowledge concerning mechanisms of chronic pain in general, no clinical guidelines exist concerning assessment, pain control and rehabilitation of patients with chronic WAD. READ MORE

  6. 4. Pathways linking sleep, neuroimmune signaling and pain: an integrative approach

    Author : Martin Flores Bjurström; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pain; neuroinflammation; inflammation; glia; central sensitization; cerebrospinal fluid; osteoarthritis; chronic postsurgical pain; groin hernia repair; sleep; sleep disturbance; perioperative; neurophysiology;

    Abstract : Background and objectives: Neuroinflammation is implicated in the development and maintenance of persistent pain states, but there is limited data linking cerebrospinal fluid (CSF) inflammatory mediators with neurophysiological pain processes in humans. Study I aimed to investigate whether there are coherent changes in CSF inflammation associated with central sensitization (CS), and to evaluate potential differences in CSF levels of inflammatory mediators between osteoarthritis (OA) patients with disabling pain and pain-free controls. READ MORE

  7. 5. A clinical image of migraine. On prevalence, impact of disease, natural course of attacks and influence of 5-HT1B/1D-agonists

    Author : Mattias Linde; Göteborgs universitet; []
    Keywords : migraine; epidemiology; Sweden; burden; quality of life; natural course; triptans; sensitization; allodynia; hyperalgesia;

    Abstract : The first, large nationwide survey of the epidemiology of migraine in Sweden was performed. The one-year prevalence is 13.2 b1.9% (16. READ MORE