Search for dissertations about: "chemometrics"

Showing result 1 - 5 of 42 swedish dissertations containing the word chemometrics.

  1. 1. Variance Reduction in Analytical Chemistry New Numerical Methods in Chemometrics and Molecular Simulation

    University dissertation from Stockholm : Institutionen för analytisk kemi

    Author : K. Magnus Åberg; Stockholms universitet.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chemometrics; pulse-coupled neural networks; peak alignment; class separability; molecular dynamics; Monte Carlo; expanded ensembles; free energy; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi;

    Abstract : This thesis is based on five papers addressing variance reduction in different ways. The papers have in common that they all present new numerical methods. READ MORE

  2. 2. Aspects of Optimisation of Separation of Drugs by Chemometrics

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Valérie Harang; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; optimisation; separation; chemometrics; high performance liquid chromatography; electrodriven techniques; microemulsion electrokinetic chromatography; statistical experimental design; molecular modelling; chiral separation; cellobiohydrolase; Farmaceutisk kemi; PHARMACY Pharmaceutical chemistry; FARMACI Farmaceutisk kemi;

    Abstract : Statistical experimental designs have been used for method development and optimisation of separation. Two reversed phase HPLC methods were optimised. READ MORE

  3. 3. Development of Protocols for Metabolomics in Biomedical Research using Chemometrics

    University dissertation from Department of Chemistry, Lund University

    Author : Anders Danielsson; Lunds universitet.; Lund University.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gas chromatography; mass spectrometry; design of experiments; Metabolomics; chemometrics; diabetes; metabolism; multivariate analysis;

    Abstract : Metabolomics is a rapidly growing research field. It aims for quantification of all the metabolites in a biological sample such as plasma, saliva, cerebrospinal fluid or cells. READ MORE

  4. 4. Advances in Separation Science . Molecular Imprinting: Development of Spherical Beads and Optimization of the Formulation by Chemometrics

    University dissertation from Stockholm : Institutionen för analytisk kemi

    Author : Henrik Kempe; Stockholms universitet.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chromatography; Parameter estimation; Diffusion; Molecularly imprinted polymer; Suspension polymerization; Chemometrics; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi;

    Abstract : An intrinsic mathematical model for simulation of fixed bed chromatography was demonstrated and compared to more simplified models. The former model was shown to describe variations in the physical, kinetic, and operating parameters better than the latter ones. READ MORE

  5. 5. Methods for structural studies of an antibody, screening metabolites in rat urine and analysis of spent cell cultivation media using LC/ESI-MS and chemometrics

    University dissertation from Stockholm : Department of Analytical Chemistry, Stockholm University

    Author : Leila Zamani; Stockholms universitet.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; analytisk kemi; Analytical Chemistry; Screening; Fingerprinting; metabolomics; Protein drugs; Mammalian Cell lines; LC ESI-MS; chemometrics;

    Abstract : This thesis describes bioanalytical methods for generating fingerprints of biological systems for extracting relevant information with (protein) drugs in focus. Similarities and differences between samples can reveal the hidden relevant information, which can be used to optimize the production and facilitate the quality control of such protein drugs during their development and manufacture. READ MORE