Search for dissertations about: "clinical correlations"

Showing result 1 - 5 of 334 swedish dissertations containing the words clinical correlations.

  2. 1. The Human Cochlea and Cochlear Implantation : Morphological Characteristics and Clinical Correlations

    Author : Nadine Schart-Morén; Helge Rask-Andersen; Elina Mäki-Torkko; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cochlear implantation; micro-CT; synchrotron; facial nerve stimulation; hearing preservation; round window;

    Abstract : The most common sensory deficit in the world is sensorineural hearing loss. Cochlear implantation (CI) can majorly contribute to restore hearing, not only in patients with severe to profound hearing loss, but also in hearing-impaired patients with residual low-frequency hearing. READ MORE

  4. 2. Clinical Pharmacogenetics of Olanzapine : with Focus on FMO Gene Polymorphisms

    Author : Mao Mao Söderberg; Marja-Liisa Dahl; Maria Gabriella Scordo; Inger Johansson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; olanzapine; pharmacogenetics; drug metabolism; schizophrenia; therapeutic drug monitoring; FMO1; FMO3; CYP1A2; UGT1A4; Clinical Pharmacology; Klinisk farmakologi;

    Abstract : Pharmacogenetics is the study of variability in drug response attributed to genetic variation. Olanzapine (OLA) is a widely used antipsychotic drug for schizophrenia treatment. The pharmacokinetics of OLA display large inter-individual variation leading to multiple-fold differences in drug exposure between patients at a given dose. READ MORE

  5. 3. Behavioral effects of female sex steroid hormones : models of PMS and PMDD in Wistar rats

    Author : Magnus Löfgren; Torbjörn Bäckström; Inga-Maj Johansson; Per Södersten; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; PMS; PMDD; rats; progesterone; estradiol; behavior; individual response; stress interaction; tolerance; withdrawal; learning and memory; anxiety.; Biological research on drug dependence; Biologisk beroendeforskning; Endocrinology; Endokrinologi; Obstetrics and gynaecology; Obstetrik och gynekologi; Pharmacological research; Farmakologisk forskning; Obstetrics and gynaecology; Obstetrik och gynekologi; Psychology; Psykologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Background Animal models can be used to mimic human conditions of psychopathology, and also as pre-clinical models to evaluate candidate drugs. With hormonal treatment it is possible to produce behavior in the rat which corresponds to the mental symptoms of pre-menstrual syndrome (PMS), and pre-menstrual dysphoric disorder (PMDD). READ MORE

  6. 4. Clinical - cytogenetic correlations in malignant hematologic disorders

    Author : Nils Mauritzson; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; treatment-related.; prognosis; gender; age; morphology; Karyotype; hematologic malignancies; extracellulära vätskor; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : In the present thesis, clinicogenetic correlations are investigated in a large population-based series of acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), acute lymphoblastic leukemia, and chronic myeloid leukemia, for which the karyotypes were analyzed at the same center. The karyotypic pattern, i.e. READ MORE

  7. 5. Effects of Clinical Pharmacists' Interventions : on Drug-Related Hospitalisation and Appropriateness of Prescribing in Elderly Patients

    Author : Ulrika Gillespie; Margareta Hammarlund-Udenaes; Claes Mörlin; Håkan Melhus; Steven Kayser; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug-related problems; medication review; appropriateness of prescribing; quality of prescribing; hospitalisation; pharmacist; clinical pharmacy; inter-professional relationships; collaboration; medication error; medication reconciliation; multidose-dispensed medications; prescription errors; transition of care; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : The overall aim of this thesis was to evaluate clinical pharmacist interventions with the focus on methods aiming to improve the quality of drug therapy and increase patient safety. Adverse drug events caused by medication errors, suboptimal dosages and inappropriate prescribing are common causes of drug-related morbidity and mortality. READ MORE