Search for dissertations about: "clinical pathways"

Showing result 1 - 5 of 680 swedish dissertations containing the words clinical pathways.

  2. 1. Hyperglycemia and Focal Brain Ischemia : Clinical and Experimental Studies

    Author : Nasim Farrokhnia; Andreas Terént; Fredrik Lennmyr; Elisabeth Björk; Henrik Hagberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; cerebrovascular disorders; diabetes mellitus; hyperglycemia; infarction; middle cerebral artery; ischemia; mitogen-activated protein kinases; mortality; rats; reactive oxygen species; reperfusion; signal transduction; therapeutics; Invärtesmedicin; Internal medicine; Invärtesmedicin;

    Abstract : Diabetes is a major risk factor for ischemic stroke and is associated with increased mortality. Additionally, hyperglycemia, a common complication in acute stroke, is associated with poor outcome. READ MORE

  4. 2. Mutant superoxide dismutase-1-caused pathogenesis in amyotrophic lateral sclerosis

    Author : Daniel Bergemalm; Stefan Marklund; Thomas Brännström; Peter Andersen; Caterina Bendotti; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD1; mitochondria; proteome; transgenic mice; inclusion; Clinical chemistry; Klinisk kemi; biokemi; Biochemistry; neurologi; Neurology; Clinical Chemistry; klinisk kemi; patologi; Pathology;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a devastating disease that affects people in their late mid-life, with fatal outcome usually within a few years. The progressive degeneration of neurons responsible for muscle movement (motor neurons) throughout the central nervous system (CNS) leads to muscle wasting and paralysis, and eventually affects respiratory function. READ MORE

  5. 3. Cisplatin-resistance and cell death in malignant pleural mesothelioma cells

    Author : Veronica Janson; Kjell Grankvist; Roger Henriksson; Parviz Behnam-Motlagh; Anders Johansson; Boris Zhivotovsky; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; BH3-only proteins; caspase; cell morphology; potassium transport; protein kinase B PKB Akt ; signalling pathways; time; Clinical chemistry; Klinisk kemi;

    Abstract : Malignant pleural mesothelioma (MPM) is an aggressive, treatment-resistant tumour. Cisplatin (cis-diamminedichloroplatinum (II)) is the best single-agent chemotherapy for MPM, but platinum-based combination therapies give the best overall response rates. However, cisplatin use is limited by resistance and severe side effects. READ MORE

  6. 4. Diffusion Tensor Imaging and Tractography of the Visual Pathways

    Author : Ylva Lilja; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diffusion tensor imaging; Visual pathways; Tractography; Temporal lobe resection; Pituitary adenomas;

    Abstract : The visual pathways are essential for human vision, stretching from the retinas of the eyes, via the anterior visual pathways and the optic radiations, to the primary visual cortex in the occipital lobe. Injury to these structures will lead to visual impairment – from small deficits to blindness. READ MORE

  7. 5. Development and evaluation of new generation vaccines against bovine respiratory syncytial virus

    Author : Krister Blodörn; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Bovine respiratory syncytial virus (BRSV) is a major cause of respiratory disease in cattle worldwide. Improved BRSV vaccines are needed, with better efficacy and longer duration of protection, in particular when used in calves with specific maternally derived antibodies (MDA). READ MORE