Search for dissertations about: "clotting factors"

Showing result 1 - 5 of 24 swedish dissertations containing the words clotting factors.

  2. 1. Proteomics of the Drosophila hemolymph clot and the function of transglutaminase

    Author : Christine Wilhelmsson; Ulrich Theopold; Iréne Söderhäll; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila; clotting; transglutaminase; innate immunity; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Abstract : Insects rely on a fast and effective coagulation and wound response to avoid loss of body fluids and immobilize pathogens. Arthropod coagulation is in some respect equivalent to vertebrate coagulation but most factors and the regulation of coagulation systems seem not to be phylogenetically conserved. READ MORE

  4. 2. Regulation of hematopoiesis in the freshwater crayfish, Pacifastacus leniusculus : role of transglutaminase

    Author : Kingkamon Junkunlo; Irene Söderhäll; Kenneth Söderhäll; Chadanat Noonin; Mats W Johansson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ast1; clotting protein; crayfish; hematopoiesis; PVF PVR; ROS; transglutaminase; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Abstract : The freshwater crayfish, Pacifastacus leniusculus, has been used as a model for studying hematopoiesis or blood cell production or hematopoiesis and immunity. The work of this thesis aims to investigate the impact of factors such as ROS signaling, Ast1, and the PVF/PVR signaling pathway in controlling stem cell behavior during hematopoiesis and specifically the role of the crosslinking enzyme transglutaminase (TGase) in regulation of hematopoiesis. READ MORE

  5. 3. Lipoprotein lipase activity is reduced in dialysis patients. Studies on possible causal factors

    Author : Dana Mahmood; Bernd Stegmayr; Gunilla Olivecrona; Per Ola Attman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haemodialysis; lipoprotein lipase; ANGPTL3; ANGPTL4; citrate dialysate; dialyzer.; medicin; Medicine;

    Abstract : Cardiovascular disease is a major cause of mortality and morbidity in patients on chronic haemodialysis (HD). One main contributing factor is renal dyslipidaemia, characterized by an impaired catabolism of triglyceride (TG)-rich lipoproteins with accumulation of atherogenic remnant particles. READ MORE

  6. 4. The role of platelets in whole blood coagulation

    Author : Sofia Ramström; Nils Olav Solum; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The body's first line of defence against bleeding is the platelets, small cell fragments with multiple roles in the coagulation process. The platelets are patrolling our blood vessels, looking for damage in the endothelial cell layer, to which they attach and transform, recruit more platelets and assemble the plasma coagulation proteases on their surfaces. READ MORE

  7. 5. Programming Blood Cell Fates. Insights from Direct Lineage Conversion and Development

    Author : Sandra Capellera Garcia; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic development; Erythropoiesis; Megakaryopoiesis; Direct Lineage Conversion;

    Abstract : Red blood cells (RBC) and platelets constitute the non-immune branch of the hematopoietic system and are responsible for the vital functions of transporting oxygen to the tissues and clotting blood vessel injuries, respectively. These cells are produced during embryonic development and throughout life through a process called hematopoiesis which is tightly regulated by extrinsic and intrinsic factors. READ MORE