Search for dissertations about: "cns white-matter"

Showing result 1 - 5 of 17 swedish dissertations containing the words cns white-matter.

  2. 1. The type IV Oligodendrocyte : experimental studies on chicken white matter

    Author : Emma S. Anderson; Arthur M. Butt; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : In mammals, islet amyloid polypeptide (IAPP) is co-produced with insulin in pancreatic ß-cells. In the chicken, the expression of IAPP in the brain is more than 10-fold higher than in the pancreas. READ MORE

  4. 2. The Human Y chromosome and its role in the developing male nervous system

    Author : Martin M. Johansson; David Skuse; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MSY; sex differences; CNV; SNP; palindrome; palindromes; gr gr duplication; gr gr deletion; b2 b3 deletion; b2 b3 duplication; blue-grey duplication; blue-grey like duplication; IR2; U3; STS; AZFa; AZFb; AZFc; Olivary nucleus; Medulla oblongata; spinal cord; white matter; Affymetrix 6.0; embryo; embryonal; haplogroup; haplogroups; R1a; R1b; R-M207; E-M96; I-M170; J-M304; G-M201; Ashkenazi; Bolivian; Chinese; SNP array; padlock probing; AMY-tree; Biologi med inriktning mot zoologisk utvecklingsbiologi; Biology with specialization in Animal Development;

    Abstract : Recent research demonstrated that besides a role in sex determination and male fertility, the Y chromosome is involved in additional functions including prostate cancer, sex-specific effects on the brain and behaviour, graft-versus-host disease, nociception, aggression and autoimmune diseases. The results presented in this thesis include an analysis of sex-biased genes encoded on the X and Y chromosomes of rodents. READ MORE

  5. 3. In vivo properties of neural stem cells after transplantation into the rat brain-Studies of phenotypic differentiation and functional integration using cell-specific labelling and electrophysiological techniques

    Author : Ulrica Englund Johansson; Peter Eriksson; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell line; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; functional integration; electrophysiology; retrograde tracing; immortalized; GFP; migration; axonal projections; glia; neuron; transplantation; stem cell. progenitor cell; CNS; Biomedical Sciences;

    Abstract : In the present thesis, we have examined the in vivo properties of in vitro expanded human and rat neural stem-and progenitor cells after transplantation into the neonatal and adult rat brain. The survival and differentiation of the grafted cells were assessed using species-specific antisera, and pre-labelling with the reporter gene green fluorescent protein (GFP). READ MORE

  6. 4. Inflammatory mechanisms in experimental CNS trauma

    Author : Jonas Isaksson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Spinal cord injury; brain injury; ICAM-1; P-selectin; iNOS; inflammation; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Traumatic brain and spinal cord injuries are important causes of premature death and permanentdisability. To improve the treatment of CNS-injured patients increased knowledge about thepathophysiological events that mediate death or dysfunction of nervous tissue is urgently needed. READ MORE

  7. 5. Studies of the Biology of Intrathecal Treatment in Progressive MS

    Author : Joakim Bergman; Anders Svenningsson; A. Tommy Bergenheim; Jonathan D. Gilthorpe; Joachim Burman; Magnus Andersson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Progressive Multiple Sclerosis; intrathecal treatment; Ommaya reservoir; anti-CD20 therapy; microdialysis; cerebrospinal fluid; CNS compartments; Progressiv Multipel Skleros; intratekal behandling; Ommaya reservoar; anti-CD20 terapi; mikrodialys; ryggmärgsvätska; sektioner i centrala nervsystemet; Neurology; neurologi;

    Abstract : Background: Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease, affecting the central nervous system (CNS). About 85% of afflicted present with a relapsing-remitting form of the disease (RRMS), for which a breakthrough in treatment was made in 2008 with rituximab, an antibody directed towards CD20, a surface antigen on B-cells. READ MORE